Evidence map›Paper›PMID 36506011›Full record

ArticleFrontiers in cellular and infection microbiology2022

Epitope profiling of monoclonal antibodies to the immunodominant antigen BmGPI12 of the human pathogen

Meenal Chand, Jae-Yeon Choi, Anasuya C Pal, Pallavi Singh, Vandana Kumari, Jose Thekkiniath, Jacqueline Gagnon, Sushma Timalsina, Gauri Gaur, Scott Williams and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Human babesiosis: The past, present and future.Expert reviews in molecular medicine · 2025
    Review
  2. Article
  3. A set of diagnostic tests for detection of active Babesia duncani infection.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2024
    Article
  4. Identification ofInfection and immunity · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Meenal ChandDepartment of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, United States.
Jae-Yeon ChoiDepartment of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, United States.
Anasuya C PalDepartment of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, United States.
Pallavi SinghDepartment of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, United States.
Vandana KumariDepartment of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, United States.
Jose ThekkiniathDepartment of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, United States.
Jacqueline GagnonL2 Diagnostics, LLC, New Haven, CT, United States.
Sushma TimalsinaL2 Diagnostics, LLC, New Haven, CT, United States.
Gauri GaurL2 Diagnostics, LLC, New Haven, CT, United States.
Scott WilliamsDepartment of Forestry and Horticulture, Connecticut Agricultural Experiment Station, New Haven, CT, United States.
Michel LedizetL2 Diagnostics, LLC, New Haven, CT, United States.
Choukri Ben MamounDepartment of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, United States.
Yale University · USConnecticut Agricultural Experiment Station · US

Funding

Fosinopril analogs for the treatment of human babesiosisR01AI153100 · NIAID · YALE UNIVERSITY · PI BEN MAMOUN, CHOUKRI · 2021 to 2025
$3.6M
An antigen-detection assay to diagnose Babesia microti infectionR44AI136118 · NIAID · L2 DIAGNOSTICS, LLC · PI LEDIZET, MICHEL · 2020 to 2022
$2.1M
An antigen-detection assay to diagnose Babesia microti infectionR43AI136118 · NIAID · L2 DIAGNOSTICS, LLC · PI LEDIZET, MICHEL · 2018 to 2018
$300k
NIAID NIH HHS R01 AI153100NIAID NIH HHS R43 AI136118NIAID NIH HHS R44 AI136118
6 · The paper itself

Abstract

The significant rise in the number of tick-borne diseases represents a major threat to public health worldwide. One such emerging disease is human babesiosis, which is caused by several protozoan parasites of the

Indexed as

BabesiaBabesia microtiGastropodaMalaria, FalciparumAnimalsAntibodies, MonoclonalEpitopesHumansImmunodominant EpitopesMammalsMiceAntibodies, MonoclonalEpitopesImmunodominant Epitopesantibodiesantigen captureapicomplexan parasiteBabesia microtiBmGPI12ELISAepitope mappinghuman babesiosis

Identifiers

PMID36506011
PMCPMC9732259
OpenAlexW4310040194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.