Evidence map›Paper›PMID 36505997›Full record

ReviewUrology annals

Management of metastatic castration-resistant prostate cancer in Middle East African countries: Challenges and strategic recommendations.

Shouki Bazarbashi, Abdullah Alsharm, Alaa Meshref, Hind Mrabti, Jawaher Ansari, Marwan Ghosn, Mohamed Abdulla, Yuksel Urun

Open access · goldAbstract readReview
In one paragraph

Review in Urology annals. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 6 countries.

Shouki BazarbashiOncology Center, King Faisal Specialist Hospital and Research Centre, King Fahad Medical City, Riyadh, Saudi Arabia.
Abdullah AlsharmComprehensive Cancer Center, King Fahad Medical City, King Fahad Medical City, Riyadh, Saudi Arabia.
Alaa MeshrefDepartment of Urology, Cairo University, Egypt.
Hind MrabtiDepartment of Medical Oncology, National Institute of Oncology, Mohamed V University-Rabat, Morocco.
Jawaher AnsariDepartment of Medical Oncology, Tawam Hospital, Al Ain, UAE.
Marwan GhosnDepartment of Medical Oncology, Saint Joseph University in Beirut, Lebanon.
Mohamed AbdullaDepartment of Clinical Oncology, Cairo University, Egypt.
Yuksel UrunDepartment of Medical Oncology, Ankara University, Turkey.
Cairo University · EGAnkara University · TRInstitut National d'Oncologie · MAKing Fahd Medical City · SAKing Faisal Specialist Hospital & Research Centre · SASaint Joseph University · LBTawam Hospital · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the reliance on Western guidelines for managing prostate cancer (PC), there are wide variations and gaps in treatment among developing countries such as the Middle East African (MEA) region. A multidisciplinary team of experts from the MEA region engaged in a comprehensive discussion to identify the real-world challenges in diagnostics and treatment of Metastatic Castration-Resistant Prostate Cancer (mCRPC) and provided insights on the urgent unmet needs. We present a consensus document on the region-specific barriers, key priority areas and strategic recommendations by experts for optimizing management of mCRPC in the MEA. Limited access to genetic testing and economic constraints were highlighted as major concerns in the MEA. As the therapeutic landscape continues to expand, treatment selection for mCRPC needs to be increasingly personalized. Enhanced genetic testing and judicious utilization of newer therapies like olaparib, articulated by reimbursement support, should be made accessible for the underserved populations in the MEA. Increasing awareness on testing through educational activities catalyzed by digital technologies can play a central role in overcoming barriers to patient care in the MEA region. The involvement of multidisciplinary teams can bridge the treatment gaps, facilitating holistic and optimal management of mCRPC. Region-specific guidelines can help health-care workers navigate challenges and deliver personalized management through collaborative efforts - thus curb health-care variations and drive consistency. Development of region-specific scalable guidelines for genetic testing and treatment of mCRPC, factoring in the trade-off for access, availability, and affordability, is crucial.

Indexed as

Genetic testingmetastatic castration-resistant prostate cancerMiddle East African regionmultidisciplinary care

Identifiers

PMID36505997
PMCPMC9731188
OpenAlexW4311282489

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.