ArticleAntimicrobial stewardship & healthcare epidemiology : ASHE2022
Clinical and occupational risk factors for coronavirus disease 2019 (COVID-19) in healthcare personnel.
Article in Antimicrobial stewardship & healthcare epidemiology : ASHE, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The trial behind it
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Who cites it
5 citing papers in PubMed.
- Impact of Occupational and Extra-Professional Exposure Across the Different Waves of the Pandemic on the Risk of SARS-CoV-2 Infection Among Healthcare Workers-The ORCHESTRA Project.Healthcare (Basel, Switzerland) · 2026Article
- Integrating deep learning and clinical characteristics for early prediction of endometrial cancer using multimodal ultrasound imaging: a multicenter study.Frontiers in oncology · 2025Article
- SARS-CoV-2 anti-N antibodies among healthcare personnel without previous known COVID-19.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2024Article
- Association between job role and coronavirus disease 2019 (COVID-19) among healthcare personnel, Iowa, 2021.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2022Article
- Optimizing Missouri's Preparation for the Next Pandemic: Lessons Learned from COVID-19: Part 1.Missouri medicineArticle
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Objective: To identify characteristics associated with positive severe acute respiratory coronavirus virus 2 (SARS-CoV-2) polymerase chain reaction (PCR) tests in healthcare personnel. Design: Retrospective cohort study. Setting: A multihospital healthcare system. Participants: Employees who reported SARS-CoV-2 exposures and/or symptoms of coronavirus disease 2019 (COVID-19) between March 30, 2020, and September 20, 2020, and were subsequently referred for SARS-CoV-2 PCR testing. Methods: Data from exposure and/or symptom reports were linked to the corresponding SARS-CoV-2 PCR test result. Employee demographic characteristics, occupational characteristics, SARS-CoV-2 exposure history, and symptoms were evaluated as potential risk factors for having a positive SARS-CoV-2 PCR test. Results: Among 6,289 employees who received SARS-CoV-2 PCR testing, 873 (14%) had a positive test. Independent risk factors for a positive PCR included: working in a patient care area (relative risk [RR], 1.82; 95% confidence interval [CI], 1.37-2.40), having a known SARS-CoV-2 exposure (RR, 1.20; 95% CI, 1.04-1.37), reporting a community versus an occupational exposure (RR, 1.87; 95% CI, 1.49-2.34), and having an infected household contact (RR, 2.47; 95% CI, 2.11-2.89). Nearly all HCP (99%) reported symptoms. Symptoms associated with a positive PCR in a multivariable analysis included loss of sense of smell (RR, 2.60; 95% CI, 2.09-3.24) or taste (RR, 1.75; 95% CI, 1.40-2.20), cough (RR, 1.95; 95% CI, 1.40-2.20), fever, and muscle aches. Conclusions: In this cohort of >6,000 healthcare system and academic medical center employees early in the pandemic, community exposures, and particularly household exposures, were associated with greater risk of SARS-CoV-2 infection than occupational exposures. This work highlights the importance of COVID-19 prevention in the community and in healthcare settings to prevent COVID-19.
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Registered trials
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