Evidence map›Paper›PMID 36505900›Full record

ArticleTransplantation direct2022

Induction in Pancreas Transplantation: T-cell Depletion Versus IL-2 Receptor Blockade.

Fahad Aziz, Sandesh Parajuli, Dixon Kaufman, Jon Odorico, Didier Mandelbrot

Open access · goldAbstract read
In one paragraph

Article in Transplantation direct, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Locus-specific HLA matching and induction therapy in simultaneous pancreas-kidney transplantation: a national UK cohort study.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Impact of Induction Therapy in Low Immunological Risk Simultaneous Pancreas-Kidney Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Fahad AzizDivision of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Sandesh ParajuliDivision of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Dixon KaufmanDivision of Transplant Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Jon OdoricoDivision of Transplant Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Didier MandelbrotDivision of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.
University of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is limited data exist on relative outcomes with T-depletion versus IL-2 receptor (IL2R) blockade induction in pancreas transplantation. Methods: We analyzed all patients who underwent simultaneous pancreas-kidney or pancreas transplant alone at our institution between January 1, 2011, and December 31, 2019. Results: Of 417 pancreas transplant recipients, 291 received induction with a T-depleting agent and 126 received induction with an IL2R blocker. No difference was detected in pancreas allograft death-censored ( Conclusion: Our data suggest that IL-2 receptor blockade may be a reasonable choice of induction for pancreas transplant recipients at low immunologic risk.

Identifiers

PMID36505900
PMCPMC9722744
OpenAlexW4311285524

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.