Evidence map›Paper›PMID 36505739›Full record

ArticleFrontiers in chemistry2022

Pyrazolyl-s-triazine with indole motif as a novel of epidermal growth factor receptor/cyclin-dependent kinase 2 dual inhibitors.

Ihab Shawish, Mohamed S Nafie, Assem Barakat, Ali Aldalbahi, Hessa H Al-Rasheed, M Ali, Walhan Alshaer, Mazhar Al Zoubi, Samha Al Ayoubi, Beatriz G De la Torre and 2 more

Erratum issuedAbstract read
In one paragraph

Article in Frontiers in chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Design, synthesis,RSC advances · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. New spiro-indeno[1,2-Journal of enzyme inhibition and medicinal chemistry · 2023
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Ihab ShawishDepartment of Math and Sciences, College of Humanities and Sciences, Prince Sultan University, Riyadh, Saudi Arabia.
Mohamed S NafieDepartment of Chemistry, Faculty of Science, Suez Canal University, Ismaïlia, Egypt.
Assem BarakatDepartment of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
Ali AldalbahiDepartment of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
Hessa H Al-RasheedDepartment of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
M AliDepartment of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
Walhan AlshaerCell Therapy Center, The University of Jordan, Amman, Jordan.
Mazhar Al ZoubiDepartment of Basic Medical Sciences, Faculty of Sciences, Yarmouk University, Irbid, Jordan.
Samha Al AyoubiDepartment of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
Beatriz G De la TorreKwaZulu-Natal Research Innovation and Sequencing Platform (KRISP) School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
Fernando AlbericioPeptide Science Laboratory, School of Chemistry and Physics, University of KwaZulu-Natal, Durban, South Africa.
Ayman El-FahamChemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of pyrazolyl-

Indexed as

anticancer profileapoptosisEGFR/CDK-2indolepyrazolyl-s-triazine

Identifiers

PMID36505739
PMCPMC9732672

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.