Evidence map›Paper›PMID 36505439›Full record

ArticleFrontiers in immunology2022

Acircadian rhythm-related gene signature for predicting survival and drug response in HNSC.

Chuan Zhang, Dan Dang, Hongrui Wang, Shuyou Shi, Jiayu Dai, Ming Yang

Abstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chuan ZhangDepartment of Pediatric Surgery, First Affiliated Hospital of Jilin University, Changchun, China.
Dan DangDepartment of Neonatology, The First Hospital of Jilin university, Changchun, China.
Hongrui WangDepartment of Molecular Biology, College of Basic Medical Sciences, Jilin University, Changchun, Jilin, China.
Shuyou ShiDepartment of Molecular Biology, College of Basic Medical Sciences, Jilin University, Changchun, Jilin, China.
Jiayu DaiCollege of Clinical Medicine, Jilin University, Changchun, Jilin, China.
Ming YangDepartment of Molecular Biology, College of Basic Medical Sciences, Jilin University, Changchun, Jilin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Head and neck squamous cell carcinoma (HNSC) represents one of the most common malignant carcinomas worldwide. Because the 5-year survival rate of patients with HNSC is poor, it is necessary to develop an effective signature for predicting the risk of HNSC. To identify a circadian rhythm (CR)-related predictive signature, we analyzed the RNA-seq data of patients with HNSC from The Cancer Genome Atlas and Gene Expression Omnibus cohorts. Nine CR-related genes (

Indexed as

CarcinomaHead and Neck NeoplasmsHumansKaplan-Meier EstimateNeoplasm Recurrence, LocalSquamous Cell Carcinoma of Head and NeckTumor Microenvironmentcircadian rhythmdrug responsegene signaturehead and neck squamous cell carcinomaprognosis

Identifiers

PMID36505439
PMCPMC9729285

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.