Evidence map›Paper›PMID 36505379›Full record

ArticleFrontiers in cardiovascular medicine2022

Neurocognitive function in patients with atrial fibrillation undergoing pulmonary vein isolation.

Leon Zwimpfer, Stefanie Aeschbacher, Philipp Krisai, Michael Coslovsky, Anne Springer, Rebecca E Paladini, Marc Girod, Janik Hufschmid, Sven Knecht, Patrick Badertscher and 9 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02105844 (Swiss Atrial Fibrillation Cohort Study - SWISS AF), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02105844 active not recruitingnot on this map

Swiss Atrial Fibrillation Cohort Study - SWISS AF

TypeobservationalSponsorUniversity Hospital, Basel, SwitzerlandRan2014 to 2030Enrolled2,415ConditionsAtrial Fibrillation
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Leon ZwimpferCardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland.
Stefanie AeschbacherCardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland.
Philipp KrisaiCardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland.
Michael CoslovskyCardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland.
Anne SpringerCardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland.
Rebecca E PaladiniCardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland.
Marc GirodCardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland.
Janik HufschmidCardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland.
Sven KnechtCardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland.
Patrick BadertscherCardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland.
Jürg H BeerDepartment of Medicine, Cantonal Hospital of Baden and Molecular Cardiology, University Hospital of Zürich, Zürich, Switzerland.
Leo H BonatiDepartment of Clinical Research, University Hospital Basel, Basel, Switzerland.
Christine S ZuernCardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland.
Laurent RotenDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Tobias ReichlinDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Christian SticherlingCardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland.
David ConenPopulation Health Research Institute, McMaster University, Hamilton, ON, Canada.
Stefan OsswaldCardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland.
Michael KühneCardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Atrial fibrillation (AF) is associated with cognitive dysfunction. However, neurocognitive function in AF patients undergoing pulmonary vein isolation (PVI) has not been well studied. The aim of this analysis is to compare neurocognitive function in patients who did or did not undergo PVI. Materials and methods: We used data from the Swiss Atrial Fibrillation Cohort study (Swiss-AF), a prospective, observational, multicenter study in Switzerland. Patients with documented AF were enrolled and data of 1,576 patients without history of PVI and with complete information on PVI status and neurocognitive function were used. Information on PVI was collected at baseline and during 1 year of follow-up. Neurocognitive testing was performed at baseline and after 1 year of follow-up, using the Montreal Cognitive Assessment (MoCA), trail making test (TMT) A and B, digit symbol substitution test (DSST) and semantic fluency test (SFT). To investigate the association of PVI with neurocognitive function, we use propensity score matching (1:3) and inverse probability of treatment weighting (IPTW). Results: The mean age of this population was 74 ± 8 years, 27.1% were women. Overall, 88 (5.5%) patients underwent PVI during 1 year of follow-up. Using ITPW ( Conclusion: In this population of AF patients, there was no consistent evidence of an association between PVI and neurocognitive function. Clinical trial registration: [https://clinicaltrials.gov/], identifier [NCT02105844].

Indexed as

atrial fibrillationinverse probability of treatment weightingMontreal Cognitive Assessmentneurocognitive functionpropensity scorepulmonary vein isolation

Identifiers

PMID36505379
PMCPMC9732530

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.