ArticleFrontiers in cardiovascular medicine2022
Coronary microvascular dysfunction as assessed by angiography-derived index of microvascular resistance co-localizes with and may explain the presence of ischemia in stress-cardiac magnetic resonance imaging in the absence of coronary artery disease.
Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 6 citations in OpenAlex.
- Prognostic impact of angiography-derived index of microcirculatory resistance in patients with dilated cardiomyopathy.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Association between the Tpeak-Tend interval on admission and coronary microvascular dysfunction in Takotsubo syndrome.ESC heart failure · 2025Article
- Coronary microvascular dysfunction is a hallmark of all subtypes of MINOCA.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Article
- The role of imaging in the selection of patients for HFpEF therapy.European heart journal. Cardiovascular Imaging · 2023Review
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7 authors at 3 institutions in 1 country.
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Abstract
Introduction: Ischemia with no obstructive coronary disease (INOCA) is a frequent phenomenon in the cath lab. A possible cause is coronary microvascular dysfunction (CMD), which may be assessed by invasive testing with possible complications; therefore, less invasive approaches have emerged, such as the angiography-derived index of microvascular resistance (aIMR). The aim of our study was to investigate the association of single-vessel aIMR as a measure of CMD with areas of INOCA in stress testing. Methods: We measured aIMR in 286 vessels from 102 patients undergoing both stress cMRI and coronary angiography. Groups were (a) INOCA group (93 vessels, 32 patients); (b) coronary artery disease (CAD) control group (116 vessels, 42 patients) with ischemia due to relevant stenosis; and (c) control group (77 vessels, 28 patients) without ischemia or relevant stenosis. Results: INOCA patients presented higher mean aIMR (28.3 ± 5.7) compared to both CAD patients (17.4 ± 5.7, Conclusion: CMD, as assessed by 3-vessel aIMR, co-localizes with and may explain the presence of ischemia in stress-cMRI in INOCA.
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