Evidence map›Paper›PMID 36505339›Full record

ArticleAmerican journal of translational research2022

The median effective concentration of remifentanil to inhibit pupillary reflex dilation induced by endotracheal intubation.

Meijuan Qian, Yue Zhao, Li Han, Lihong Zhao, Fen Yang, Hong Xie, Yang Xie

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 70% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Meijuan QianDepartment of Anesthesiology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School of Nanjing Medical University Suzhou 215002, Jiangsu, China.
Yue ZhaoDepartment of Anesthesiology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School of Nanjing Medical University Suzhou 215002, Jiangsu, China.
Li HanDepartment of Anesthesiology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School of Nanjing Medical University Suzhou 215002, Jiangsu, China.
Lihong ZhaoDepartment of Anesthesiology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School of Nanjing Medical University Suzhou 215002, Jiangsu, China.
Fen YangDepartment of Anesthesiology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School of Nanjing Medical University Suzhou 215002, Jiangsu, China.
Hong XieDepartment of Anesthesiology and Critical Care, The Second Affiliated Hospital of Soochow University Suzhou 215008, Jiangsu, China.
Yang XieDepartment of Anesthesiology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School of Nanjing Medical University Suzhou 215002, Jiangsu, China.
Suzhou Municipal Hospital · CNSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the median effective concentration (EC

methodsIn this prospective study, 34 patients undergoing elective surgery under general anesthesia were selected. The induction of anesthesia was started using propofol with an effect-site concentration (Ce(pro)) of 4.0 μg/mL. The effect-site concentration of remifentanil (Ce(Remi)) was set according to the modified sequential test method, with 0.42 ng/mL as the initial concentration for the first patient. The gradient ratio was 1.1. The Ce(Remi) of each patient was determined by whether the PRD of the previous patient disappeared during endotracheal intubation. If the PRD disappeared, a lower concentration was applied. Otherwise, a higher concentration was applied. The experiment ended after 9 crosses of PRD disappearance-presence and PRD presence-disappearance. The EC

resultsThe EC

conclusionThe EC

Indexed as

endotracheal intubationpupilsremifentanilsequential methodUltrasound

Identifiers

PMID36505339
PMCPMC9730105
OpenAlexW4311288690

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.