Evidence map›Paper›PMID 36505319›Full record

ReviewAmerican journal of translational research2022

Phytochemicals and modulation of exercise-induced oxidative stress: a novel overview of antioxidants.

Nancy Vargas-Mendoza, Ángel Morales-González, Eduardo Osiris Madrigal-Santillán, Marcelo Angeles-Valencia, Liliana Anguiano-Robledo, Laura Ligia González-López, Alejandra Sosa-Gómez, Tomás Fregoso-Aguilar, Cesar Esquivel-Chirino, Yahel Anahí Ruiz-Velazco-Benítez and 1 more

Open access · greenAbstract readReview
In one paragraph

Review in American journal of translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Acute Effects ofFoods (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Nancy Vargas-MendozaLaboratorio de Medicina de Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional Ciudad de Mexico, Mexico.
Ángel Morales-GonzálezEscuela Superior de Cómputo, Instituto Politécnico Nacional Ciudad de Mexico, Mexico.
Eduardo Osiris Madrigal-SantillánLaboratorio de Medicina de Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional Ciudad de Mexico, Mexico.
Marcelo Angeles-ValenciaLaboratorio de Medicina de Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional Ciudad de Mexico, Mexico.
Liliana Anguiano-RobledoEscuela Superior de Medicina, Laboratorio de Farmacología Molecular, Instituto Politécnico Nacional Ciudad de Mexico, Mexico.
Laura Ligia González-LópezCentro Interdisciplinario de Ciencias de la Salud Unidad Santo Tomas, Instituto Politécnico Nacional Ciudad de Mexico, Mexico.
Alejandra Sosa-GómezCentro Interdisciplinario de Ciencias de la Salud Unidad Santo Tomas, Instituto Politécnico Nacional Ciudad de Mexico, Mexico.
Tomás Fregoso-AguilarLaboratorio de Hormonas y Conducta, Departamento de Fisiología, ENCB Campus Zacatenco, Instituto Politécnico Nacional Ciudad de Mexico, Mexico.
Cesar Esquivel-ChirinoÁrea de Básicas Médicas, División de Estudios Profesionales, Facultad de Odontología, Universidad Nacional Autónoma de México Ciudad de Mexico, Mexico.
Yahel Anahí Ruiz-Velazco-BenítezServicio de Medicina Materno Fetal, UMAE HGO No. 3 CMN "La Raza" IMSS. Ciudad de Mexico, Mexico.
José A Morales-GonzálezLaboratorio de Medicina de Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional Ciudad de Mexico, Mexico.
Instituto Politécnico Nacional · MXCentro Médico Nacional La Raza · MXUniversidad Autónoma de la Ciudad de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The practice of physical exercise induces a series of physiological changes in the body at different levels, either acutely or chronically. During exercise, the increase in oxygen consumption promotes the production of reactive oxygen species (ROS) and reactive nitrogen species (RNS), which are necessary to maintain homeostasis. ROS/RNS activate cellular signaling pathways, such as the antioxidant cytoprotective systems, inflammation, and cell proliferation, which are crucial for cell survival. However, in exhaustive-extended physical exercise, workloads can exceed the endogenous antioxidant defenses, which may be related to impairment of muscle contraction, fatigue, and a decrease in athletic performance. This review addresses the role of some antioxidants from plant-derived extracts called phytochemicals that can mediate the response to oxidative stress induced by physical exercise by activating signaling pathways, such as Nrf2/Keap1/ARE, responsible for the endogenous antioxidant response and possibly having an impact on sports performance.

Indexed as

antioxidantsmuscle contractionNrf2Oxidative stressperformancephysical exercisephytochemicals

Identifiers

PMID36505319
PMCPMC9730074
OpenAlexW4311289863

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.