Evidence map›Paper›PMID 36505301›Full record

ArticleAmerican journal of translational research2022

Effects of Tegafur, Gimeracil and Oteracil Potassium Capsules combined with Calf Spleen Extractive Injection on serum VEGF and MMP-9 in patients with advanced gastric cancer.

Yan Zhang, Qiang Zhong, Xiaochun Luo, Wei Zhang

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Yan ZhangDepartment of Gastroenterology, Xiamen Humanity Hospital, Fujian Medical University Xiamen, Fujian, China.
Qiang ZhongDepartment of Anesthesiology, Xiang'an Hospital of Xiamen University Xiamen, Fujian, China.
Xiaochun LuoCenter for Digestive Endoscopy, Xiang'an Hospital of Xiamen University Xiamen, Fujian, China.
Wei ZhangThe First Department of Surgery, Anyang Tumor Hospital Anyang, Henan, China.
Xiamen University · CNAnyang Tumor Hospital · CNFujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the effects of Tegafur, Gimeracil and Oteracil Potassium Capsules (TGOPC) combined with Calf Spleen Extractive Injection (CSEI) on vascular endothelial growth factor (VEGF) and matrix metalloproteinase-9 (MMP-9) in patients with advanced gastric cancer.

methodsA retrospective analysis was conducted on data of 118 patients with advanced gastric cancer treated in Anyang Tumor Hospital from January 2016 to September 2018. The patients were divided into two groups according to treatment modalities, with control group receiving Oxaliplatin and TGOPC and observation group receiving Oxaliplatin, TGOPC and CSEI. Clinical efficacy, changes of serum VEGF and MMP-9 before and after chemotherapy, survival rate and incidence of adverse reactions were compared between the two groups.

resultsThe number of responded patients was 36 (61.02%) in the observation group and was 18 (30.51%) in the control group (

conclusionThe use of CSEI on the basis of Oxaliplatin combined with TGOPC chemotherapy for the treatment of advanced gastric cancer could further improve the clinical efficacy and survival rate, and reduce the incidence of adverse reactions.

Indexed as

Advanced gastric cancerCalf Spleen Extractive InjectionGimeracil and Oteracil Potassium Capsulesmatrix metalloproteinase-9OxaliplatinTegafurvascular endothelial growth factor

Identifiers

PMID36505301
PMCPMC9730097
OpenAlexW4311290149

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.