Evidence map›Paper›PMID 36505248›Full record

ArticleFrontiers in nutrition2022

Muscle mass loss is associated with physical dysfunction in patients with early rheumatoid arthritis.

Jie Pan, Yao-Wei Zou, Ying-Ying Zhu, Jian-Zi Lin, Tao Wu, Ze-Hong Yang, Xue-Pei Zhang, Qian Zhang, Hu-Wei Zheng, Xiao-Ling He and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 16 citations in OpenAlex.

  1. Longitudinal Course of Muscle Status in Patients With Rheumatoid Arthritis.International journal of rheumatic diseases · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Observational
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Jie PanDepartment of Rheumatology, Sun Yat-Sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Yao-Wei ZouDepartment of Rheumatology, Sun Yat-Sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Ying-Ying ZhuDivision of Clinical Research Design, Sun Yat-Sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Jian-Zi LinDepartment of Rheumatology, Sun Yat-Sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Tao WuDepartment of Rheumatology, Sun Yat-Sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Ze-Hong YangDepartment of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Xue-Pei ZhangDepartment of Rheumatology, Sun Yat-Sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Qian ZhangDepartment of Rheumatology, Sun Yat-Sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Hu-Wei ZhengDepartment of Rheumatology, Sun Yat-Sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Xiao-Ling HeShanghai Healthcare Co. Ltd., Zhangjiang Innopark, Shanghai, China.
Wan-Mei ChengShanghai Healthcare Co. Ltd., Zhangjiang Innopark, Shanghai, China.
Jian-Da MaDepartment of Rheumatology, Sun Yat-Sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Lie DaiDepartment of Rheumatology, Sun Yat-Sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Sun Yat-sen University · CNSun Yat-sen Memorial Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Muscle mass loss is common in long-standing rheumatoid arthritis (RA). The aim was to explore the prevalence and effects of RA disease characteristics in patients with early RA. Methods: This cross-sectional study was carried out based on a Chinese RA cohort and control subjects. The body composition (BC) was assessed using bioelectric impedance analysis. Myopenia was defined by an appendicular skeletal muscle mass index of ≤ 7.0 kg/m Results: In total, 2017 controls and 1,008 patients with RA were recruited for this study. Among the patients with RA, there were 190 (18.8%) patients with early RA, with a median disease duration of 7 (4, 11) months. The matched patients with early RA ( Conclusion: Our data indicate the importance of early detection of muscle involvement in the early stage of RA and imply the significance of early aggressive control of disease activity for the prevention of myopenia and physical dysfunction in patients with early RA. Our study provides a new perspective on RA management.

Indexed as

body compositionearly rheumatoid arthritisinflammationmuscle mass lossphysical dysfunction

Identifiers

PMID36505248
PMCPMC9727302
OpenAlexW4309713907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.