Evidence map›Paper›PMID 36505110›Full record

ArticleCureus2022

Methylene Blue in Refractory Shock.

Som N Chalise, Taaliba A Sahib, Gregory A Boyer, Vikas Pathak

Registry-linked trialOpen access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06005558 (Comparative Study Between High and Low Dose Methylene Blue Infusion in Septic Cancer Patients. A Randomized Blinded Controlled Study), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06005558 phase2 / phase3completednot on this mapstarted 2023, after this paper: background citation

Comparative Study Between High and Low Dose Methylene Blue Infusion in Septic Cancer Patients. A Randomized Blinded Controlled Study

TypeinterventionalSponsorNational Cancer Institute, EgyptRan2023 to 2024Enrolled90ConditionsSeptic ShockArmsNormal saline, Methylene Blue low dose, Methylene Blue high dose
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Som N ChalisePulmonary and Critical Care Medicine, Riverside Health System, Newport News, USA.
Taaliba A SahibPulmonary and Critical Care Medicine, Riverside Health System, Newport News, USA.
Gregory A BoyerEmergency Medicine, Riverside Health System, Newport News, USA.
Vikas PathakPulmonary and Critical Care Medicine, Riverside Health System, Newport News, USA.
Riverside Regional Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many patients suffer shock in intensive care units (ICU). The majority of the patients with shock respond to standard treatment with vasopressors in addition to the treatment of underlying etiology. Some may not respond to vasopressors and have high mortality. To those patients who do not respond, methylene blue has been used in the past with some success. We present a case report on the use of methylene blue along with a brief literature review.

Indexed as

methylene blue infusionnitric oxide-cgmp pathwayoverdoserefractory shockvasoplegia

Identifiers

PMID36505110
PMCPMC9728991
OpenAlexW4308317888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.