Evidence map›Paper›PMID 36504903›Full record

ArticleAmerican journal of cancer research2022

Combination treatment of arsenic trioxide and osimertinib in recurrent and metastatic head and neck squamous cell carcinoma.

Ching-Yun Hsieh, Wei-Chao Chang, Ching-Chan Lin, Jong-Hang Chen, Chen-Yuan Lin, Chia-Hua Liu, Chen Lin, Mien-Chie Hung

Open access · greenAbstract read
In one paragraph

Article in American journal of cancer research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ching-Yun HsiehDivision of Hematology and Oncology, Department of Internal Medicine, China Medical University Hospital, China Medical University Taichung 40402, Taiwan.
Wei-Chao ChangCenter for Molecular Medicine, China Medical University Hospital, China Medical University Taichung 40402, Taiwan.
Ching-Chan LinDivision of Hematology and Oncology, Department of Internal Medicine, China Medical University Hospital, China Medical University Taichung 40402, Taiwan.
Jong-Hang ChenDivision of Hematology and Oncology, Department of Internal Medicine, China Medical University Hospital, China Medical University Taichung 40402, Taiwan.
Chen-Yuan LinDivision of Hematology and Oncology, Department of Internal Medicine, China Medical University Hospital, China Medical University Taichung 40402, Taiwan.
Chia-Hua LiuDivision of Hematology and Oncology, Department of Internal Medicine, China Medical University Hospital, China Medical University Taichung 40402, Taiwan.
Chen LinCenter for Molecular Medicine, China Medical University Hospital, China Medical University Taichung 40402, Taiwan.
Mien-Chie HungCenter for Molecular Medicine, China Medical University Hospital, China Medical University Taichung 40402, Taiwan.
China Medical University · TWAsia University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recurrent and/or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) represents an advanced stage of the disease and frequently shows resistance to these current treatments, including platinum chemotherapy, cetuximab plus chemotherapy, and checkpoint inhibitors. EGFR overexpression and

Indexed as

arsenic trioxideDNA damage responseHead and neck squamous cell carcinomaosimertinib

Identifiers

PMID36504903
PMCPMC9729903
OpenAlexW4311287227

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.