Evidence map›Paper›PMID 36504837›Full record

ArticleFrontiers in veterinary science2022

Genome-wide association study reveals novel candidate genes for litter size in Markhoz goats.

Peyman Mahmoudi, Amir Rashidi, Anahit Nazari-Ghadikolaei, Jalal Rostamzadeh, Mohammad Razmkabir, Heather Jay Huson

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  5. Review
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  8. Potential Candidate Genes Associated with Litter Size in Goats: A Review.Animals : an open access journal from MDPI · 2025
    Review
  9. Article
  10. Article
  11. Article
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  13. Incorporating new technologies in breeding plans for South African goats in harsh environments.Animal frontiers : the review magazine of animal agriculture · 2023
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Peyman MahmoudiDepartment of Animal Science, Faculty of Agriculture, University of Kurdistan, Sanandaj, Iran.
Amir RashidiDepartment of Animal Science, Faculty of Agriculture, University of Kurdistan, Sanandaj, Iran.
Anahit Nazari-GhadikolaeiDepartment of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Jalal RostamzadehDepartment of Animal Science, Faculty of Agriculture, University of Kurdistan, Sanandaj, Iran.
Mohammad RazmkabirDepartment of Animal Science, Faculty of Agriculture, University of Kurdistan, Sanandaj, Iran.
Heather Jay HusonDepartment of Animal Science, Cornell University, Ithaca, NY, United States.
University of Kurdistan · IRCornell University · USSwedish University of Agricultural Sciences · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The Markhoz goat is the only breed that can produce high-quality fiber called mohair in Iran; however, the size of its population has faced a dramatic decline during the last decades, mainly due to the reluctance of farmers to rear Markhoz goats caused by a reduction in goat production income. Litter size at birth (LSB) and weaning (LSW) are two economically important reproductive traits for local goat breeders and have the potential of increasing the population growth rate. The present study was aimed to identify possible genomic regions that are associated with LSB and LSW in Markhoz goats using a genome-wide association study (GWAS). Methods: To this end, 136 Markhoz goats with record(s) of kidding were selected for GWAS using the Illumina Caprine 50K bead chip. The individual breeding values (BV) of available LSB and LSW records estimated under an animal mixed model were used as the dependent variable in the GWAS, thereby incorporating repeated categorical variables of litter size. Results: Four SNPs on chromosomes 2, 20 and 21 were identified to be significantly associated (FDR Conclusion: These findings warrant further investigation for use in marker-assisted selection programs in Markhoz goats.

Indexed as

genome-wide association studylitter sizeMarkhoz goatprolificacyreproduction

Identifiers

PMID36504837
PMCPMC9727218
OpenAlexW4309840119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.