Observational studyPain research & management2022
Prevalence and Characterization of Psychological Trauma in Patients with Fibromyalgia: A Cross-Sectional Study.
Observational study in Pain research & management, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- The association between violence against women and chronic pain: a systematic review and meta-analysis.BMC women's health · 2024Pooled it
- Pooled it
- Fibromyalgia in obstructive sleep apnea-hypopnea syndrome: a systematic review and meta-analysis.Frontiers in physiology · 2024Pooled it
- New Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study.Arthritis care & research · 2026Article
- Peritraumatic C-reactive protein levels predict pain outcomes following traumatic stress exposure in a sex-dependent manner.The journal of pain · 2026Article
- Modulation of pain by affective touch: effects of childhood trauma, depression, chronic pain, and spinal segment.The Journal of physiology · 2026Article
- Distinct effects of fibromyalgia pain, depression and anxiety on perception of affective touch and pain.The Journal of physiology · 2026Article
- Loneliness is associated with depression, anxiety, pain, and suffering in fibromyalgia: results from a structural equation modeling analysis.Rheumatology international · 2026Observational
- Impact of Post-Traumatic Stress Disorder Management Through Reconsolidation Therapy on Fibromyalgia Syndrome: A Pilot Study.Biomedicines · 2026Article
- Low dose naltrexone for fibromyalgia: case series demonstrating pain relief and other health benefits.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- Towards a better definition of nociplastic pain conditions: a psychological grounded study on fibromyalgia, chronic headache and vulvodynia.European journal of psychotraumatology · 2025Article
- Trauma and psychological impact in fibromyalgia and other central sensitization syndromes: the role of anxiety and pain acceptance.BMC psychology · 2025Article
- Central Sensitization Syndromes and Trauma: Mediating Role of Sleep Quality, Pain Catastrophizing, and Emotional Dysregulation Between Post-Traumatic Stress Disorder and Pain.Healthcare (Basel, Switzerland) · 2025Article
- Efficacy of hyperbaric oxygen therapy in treating fibromyalgia linked to childhood trauma after late-onset and over a decade of symptoms: a case report.Journal of medical case reports · 2025Article
- Childhood abuse and health outcomes in patients with fibromyalgia: a cross-sectional exploratory study of the moderating effects of pain catastrophizing and mindfulness.BMC musculoskeletal disorders · 2025Article
- EEG connectivity features associated with fibromyalgia revealed by machine learning.Frontiers in pain research (Lausanne, Switzerland) · 2025Article
- Article
- Disease Phenotypes in Refractory Musculoskeletal Pain Syndromes Identified by Unsupervised Machine Learning.ACR open rheumatology · 2024Article
- Fibromyalgia and Skin Disorders: A Systematic Review.Journal of clinical medicine · 2024Review
- Unraveling the Complexity: Exploring the Intersection of Panic Disorder, Dissociation, and Complex Post-Traumatic Stress Disorder.Behavioral sciences (Basel, Switzerland) · 2024Article
Corrections and comments
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Authors and funding
14 authors at 7 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Preliminary evidence suggests that psychological trauma, especially childhood trauma, is a risk factor for the onset of fibromyalgia (FM). Objective: The main objective of this study consisted of evaluating the prevalence and detailed characteristics of psychological trauma in a sample of patients with FM, the chronology of trauma across the lifespan, and its clinical symptoms. We also calculated whether childhood trauma could predict the relationship with different clinical variables. Method: Eighty-eight females underwent an interview to assess sociodemographic data, psychiatric comorbidities, level of pain, FM impact, clinical symptoms of anxiety, depression, insomnia, quality of life, and psychological trauma. Results: The majority of participants (71.5%) met the diagnostic criteria for current post-traumatic stress disorder (PTSD). Participants reported having suffered traumatic events throughout their lifespan, especially in childhood and early adolescence, in the form of emotional abuse, emotional neglect, sexual abuse, and physical abuse. Traumatic events predict both poor quality of life and a level of pain in adulthood. All patients showed clinically relevant levels of anxiety, depression, insomnia, suicidal thoughts, and pain, as well as somatic comorbidities and poor quality of life. Pain levels predicted anxiety, depression, dissociation, and insomnia symptoms. 84% of the sample suffered one or more traumatic events prior to the onset of pain. Conclusions: Our data highlight the clinical complexity of patients with FM and the role of childhood trauma in the onset and maintenance of FM, as well as the high comorbidity between anxiety, depression, somatic symptoms, and FM. Our data also supports FM patients experiencing further retraumatization as they age, with an extremely high prevalence of current PTSD in our sample. These findings underscore the need for multidisciplinary programs for FM patients to address their physical pain and their psychiatric and somatic conditions, pay special attention to the assessment of psychological trauma, and provide trauma-focused interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.