Evidence map›Paper›PMID 36504677›Full record

ArticleFrontiers in molecular neuroscience2022

The AMPylase FIC-1 modulates TGF-β signaling in

Mirella A Hernandez-Lima, Margaret Champion, Zachary Mattiola, Matthias C Truttmann

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in molecular neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. AMPylation: key roles in biological regulation across prokaryotes and eukaryotes.Frontiers in cellular and infection microbiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mirella A Hernandez-LimaNeuroscience Graduate Program, University of Michigan, Ann Arbor, MI, United States.
Margaret ChampionDepartment of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, United States.
Zachary MattiolaDepartment of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, United States.
Matthias C TruttmannNeuroscience Graduate Program, University of Michigan, Ann Arbor, MI, United States.
University of Michigan–Ann Arbor · US

Funding

Research Training in BiogerontologyT32AG000114 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SCOTT PLETCHER · 1985 to 2026
$12.4M
Conserved regulation of proteostasis by post-translational protein AMPylationR35GM142561 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Matthias Christof Truttmann · 2021 to 2026
$2.8M
Chemosensation of death conspecifics modulates neural signaling and lifespan in Caenorhabditis elegansF31DC020397 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HERNANDEZ, MIRELLA · 2022 to 2023
$62k
NIA NIH HHS T32 AG000114NIDCD NIH HHS F31 DC020397NIGMS NIH HHS R35 GM142561
6 · The paper itself

Abstract

Post-translational protein modifications are essential for the spatio-temporal regulation of protein function. In this study, we examine how the activity of the

Indexed as

AMPylation/adenylylationchaperonesFIC activityproteostasistransforming growth factor

Identifiers

PMID36504677
PMCPMC9730714
OpenAlexW4309858922

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.