Evidence map›Paper›PMID 36504624›Full record

ArticleFrontiers in human neuroscience2022

Twenty-four-hour time-use composition and cognitive function in older adults: Cross-sectional findings of the ACTIVate study.

Maddison L Mellow, Dorothea Dumuid, Alexandra T Wade, Ty Stanford, Timothy S Olds, Frini Karayanidis, Montana Hunter, Hannah A D Keage, Jillian Dorrian, Mitchell R Goldsworthy and 1 more

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in human neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 4 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Impact of Different Types of Sedentary Behaviour on Cognitive Function in Older Adults: A Systematic Review.Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals · 2026
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  15. 24-hour activity cycle behaviors and gray matter volume in mild cognitive impairment.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Maddison L MellowAlliance for Research in Exercise, Nutrition and Activity, Allied Health and Human Performance, University of South Australia, Adelaide, SA, Australia.
Dorothea DumuidAlliance for Research in Exercise, Nutrition and Activity, Allied Health and Human Performance, University of South Australia, Adelaide, SA, Australia.
Alexandra T WadeAlliance for Research in Exercise, Nutrition and Activity, Allied Health and Human Performance, University of South Australia, Adelaide, SA, Australia.
Ty StanfordAlliance for Research in Exercise, Nutrition and Activity, Allied Health and Human Performance, University of South Australia, Adelaide, SA, Australia.
Timothy S OldsAlliance for Research in Exercise, Nutrition and Activity, Allied Health and Human Performance, University of South Australia, Adelaide, SA, Australia.
Frini KarayanidisFunctional Neuroimaging Laboratory, School of Psychological Sciences, The University of Newcastle, Newcastle, NSW, Australia.
Montana HunterFunctional Neuroimaging Laboratory, School of Psychological Sciences, The University of Newcastle, Newcastle, NSW, Australia.
Hannah A D KeageBehaviour-Brain-Body Research Centre, Justice and Society, University of South Australia, Adelaide, SA, Australia.
Jillian DorrianBehaviour-Brain-Body Research Centre, Justice and Society, University of South Australia, Adelaide, SA, Australia.
Mitchell R GoldsworthyLifespan Human Neurophysiology Group, School of Biomedicine, University of Adelaide, Adelaide, SA, Australia.
Ashleigh E SmithAlliance for Research in Exercise, Nutrition and Activity, Allied Health and Human Performance, University of South Australia, Adelaide, SA, Australia.
University of South Australia · AUUniversity of Newcastle Australia · AUSouth Australian Health and Medical Research Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Physical activity, sedentary behaviour and sleep are associated with cognitive function in older adults. However, these behaviours are not independent, but instead make up exclusive and exhaustive components of the 24-h day. Few studies have investigated associations between 24-h time-use composition and cognitive function in older adults. Of these, none have considered how the quality of sleep, or the context of physical activity and sedentary behaviour may impact these relationships. This study aims to understand how 24-h time-use composition is associated with cognitive function across a range of domains in healthy older adults, and whether the level of recreational physical activity, amount of television (TV) watching, or the quality of sleep impact these potential associations. Methods: 384 healthy older adults (age 65.5 ± 3.0 years, 68% female, 63% non-smokers, mean education = 16.5 ± 3.2 years) participated in this study across two Australian sites (Adelaide, Results: After adjusting for covariates and false discovery rate there were no significant associations between time-use composition and global cognition, long-term memory, short-term memory, executive function, or processing speed outcomes, and no significant interactions between TV watching time, recreational physical activity engagement or sleep quality and time-use composition for any cognitive outcomes. Discussion: The findings highlight the importance of considering all activities across the 24-h day against cognitive function in older adults. Future studies should consider investigating these relationships longitudinally to uncover temporal effects.

Indexed as

ageingcognitive functionphysical activitysedentary behavioursleeptime use

Identifiers

PMID36504624
PMCPMC9729737
OpenAlexW4309845597

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.