Evidence map›Paper›PMID 36504553›Full record

ReviewWorld journal of gastroenterology2022

Development of Epstein-Barr virus-associated gastric cancer: Infection, inflammation, and oncogenesis.

Hisashi Iizasa, Andy Visi Kartika, Sintayehu Fekadu, Shunpei Okada, Daichi Onomura, Afifah Fatimah Azzahra Ahmad Wadi, Mosammat Mahmuda Khatun, Thin Myat Moe, Jun Nishikawa, Hironori Yoshiyama

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Therapeutic, preventive, and pathogenetic advances in viral hepatitis.Frontiers in cellular and infection microbiology · 2026
    Review
  6. Co-infection ofJournal of virology · 2025
    Article
  7. Dihydrotestosterone-androgen receptor signaling suppresses EBV-positive gastric cancer through DNA demethylation-mediated viral reactivation.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2025
    Article
  8. Article
  9. Relationship betweenWorld journal of clinical oncology · 2025
    Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. World journal of gastrointestinal oncology · 2024
    Article
  15. Review
  16. Review
  17. Article
  18. Aging · 2024
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Hisashi IizasaDepartment of Microbiology, Shimane University Faculty of Medicine, Izumo 693-8501, Shimane, Japan.
Andy Visi KartikaDepartment of Microbiology, Shimane University Faculty of Medicine, Izumo 693-8501, Shimane, Japan.
Sintayehu FekaduDepartment of Microbiology, Shimane University Faculty of Medicine, Izumo 693-8501, Shimane, Japan.
Shunpei OkadaDepartment of Microbiology, Shimane University Faculty of Medicine, Izumo 693-8501, Shimane, Japan.
Daichi OnomuraDepartment of Microbiology, Shimane University Faculty of Medicine, Izumo 693-8501, Shimane, Japan.
Afifah Fatimah Azzahra Ahmad WadiDepartment of Microbiology, Shimane University Faculty of Medicine, Izumo 693-8501, Shimane, Japan.
Mosammat Mahmuda KhatunDepartment of Microbiology, Shimane University Faculty of Medicine, Izumo 693-8501, Shimane, Japan.
Thin Myat MoeDepartment of Microbiology, Shimane University Faculty of Medicine, Izumo 693-8501, Shimane, Japan.
Jun NishikawaFaculty of Laboratory Science, Yamaguchi University Graduate School of Medicine, Ube 755-8505, Japan.
Hironori YoshiyamaDepartment of Microbiology, Shimane University Faculty of Medicine, Izumo 693-8501, Shimane, Japan. yosiyama@med.shimane-u.ac.jp.
Yamaguchi University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epstein-Barr virus (EBV)-associated gastric cancer (EBVaGC) cells originate from a single-cell clone infected with EBV. However, more than 95% of patients with gastric cancer have a history of

Indexed as

Epstein-Barr Virus InfectionsHelicobacter pyloriStomach NeoplasmsCarcinogenesisCell Transformation, NeoplasticHerpesvirus 4, HumanHumansInflammationCoreceptorEpstein-Barr virusEpstein-Barr virus-associated gastric cancerHelicobacter pyloriInflammationOncogenesis

Identifiers

PMID36504553
PMCPMC9730441
OpenAlexW4310122768

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.