Evidence map›Paper›PMID 36504486›Full record

ReviewJournal of oral biology and craniofacial research

Microbiome and the inflammatory pathway in peri-implant health and disease with an updated review on treatment strategies.

Fathima Banu Raza, Sivakumar Vijayaragavalu, Ruckmani Kandasamy, Venkateshwaran Krishnaswami, Anand Kumar V

Abstract readReview
In one paragraph

Review in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Innovative Smart Materials in Restorative Dentistry.Journal of functional biomaterials · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fathima Banu RazaDepartment of Prosthodontics, Faculty of Dental Sciences, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Sivakumar VijayaragavaluDepartment of Life Sciences, Manipur University, Imphal, Manipur, India.
Ruckmani KandasamyCentre for Excellence in Nanobio Translational REsearch (CENTRE), Department of Pharmaceutical Technology, University College of Engineering, Anna University, BIT Campus, Tiruchirappalli, Tamil Nadu, India.
Venkateshwaran KrishnaswamiCentre for Excellence in Nanobio Translational REsearch (CENTRE), Department of Pharmaceutical Technology, University College of Engineering, Anna University, BIT Campus, Tiruchirappalli, Tamil Nadu, India.
Anand Kumar VDepartment of Prosthodontics, Faculty of Dental Sciences, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Crestal bone preservation around the dental implant for aesthetic and functional success is widely researched and documented over a decade. Several etiological factors were put forth for crestal bone loss; of which biofilm plays a major role. Biofilm is formed by the colonization of wide spectra of bacteria inhabited around dental implants. Bacterial adherence affects the regulators of bone growth and an early intervention preserves the peri-implant bone. Primary modes of therapy stated in early literature were either prevention or treatment of infection caused by biofilm. This narrative review overviews the microbiome during different stages of peri-implant health, the mechanism of bone destruction, and the expression of the biomarkers at each stage. Microbial contamination and the associated biomarkers varied depending on the stage of peri-implant infection. The comprehensive review helps in formulating a research plan, both in diagnostics and treatment aspects in improving peri-implant health.

Indexed as

AntibioticsBiomarkersCD14, Cluster of Differentiation 14CSF, Colony-Stimulating FactorGene expressionIL, InterleukinsMicrobiotaMMP 8, Matrix MetalloProteinase 8OPG, OsteoprotegerinPeri-implantPSMB 2, Proteasome subunit beta type-2RANKL, Receptor Activator of Nuclear factor Kappa-ΒLigandRANK, Receptor Activator of Nuclear factor Kappa-ΒsRANKL, soluble Receptor Activator of Nuclear Factor-κB LigandTIMP, Tissue inhibitor of MetalloproteinaseTNF, Tumor Necrosis FactorTWEAK, TNF-related weak inducer of apoptosisVEGF, Vascular Endothelial Growth Factor

Identifiers

PMID36504486
PMCPMC9730223

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.