Evidence map›Paper›PMID 36503889›Full record

ArticleBrain research2023

Expression of c-Fos following voluntary ingestion of a novel or familiar taste in rats.

Jan Wiaderkiewicz, Steve Reilly

Open access · greenAbstract read
In one paragraph

Article in Brain research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jan WiaderkiewiczDepartment of Psychology, University of Illinois at Chicago, 1007 West Harrison Street, Chicago, IL 60607, United States. Electronic address: jwiader@uic.edu.
Steve ReillyDepartment of Psychology, University of Illinois at Chicago, 1007 West Harrison Street, Chicago, IL 60607, United States. Electronic address: sreilly@uic.edu.
University of Illinois Chicago · US

Funding

Parabrachial-Forebrain Interactions in CTAR01DC006456 · NIDCD · UNIVERSITY OF ILLINOIS AT CHICAGO · PI REILLY, STEPHEN · 2004 to 2020
$3.9M
Parabrachial-Forebrain Interactions in Conditioned Taste AversionR56DC006456 · NIDCD · UNIVERSITY OF ILLINOIS AT CHICAGO · PI REILLY, STEPHEN · 2009 to 2009
$339k
NIDCD NIH HHS R01 DC006456NIDCD NIH HHS R56 DC006456
6 · The paper itself

Abstract

Taste neophobia, the rejection of novel tastes or foods, involves an interplay of various brain regions encompassing areas within the central gustatory system, as well as nuclei serving other functions. Previous findings, utilising c-Fos imaging, identified several brain regions which displayed higher activity after ingestion of a novel taste as compared to a familiar taste. The present study extends this analysis to include additional regions suspected of contributing to the neurocircuitry involved in evoking taste neophobia. Our data show increased c-Fos expression in the basolateral amygdala, central nucleus of the amygdala, gustatory portion of the thalamus, gustatory portion of the insular cortex and the medial and lateral regions of the parabrachial nucleus. These results confirm the contribution of areas previously identified as active during ingestion of novel tastes and expose additional areas that express elevated levels of c-Fos under these conditions, thus adding to the neural network involved in the detection and initial processing of taste novelty.

Indexed as

TasteTaste PerceptionAnimalsAvoidance LearningBrainEatingProto-Oncogene Proteins c-fosRatsProto-Oncogene Proteins c-fosc-FosInnate aversive responseNeophobic reactionRatUnknown taste

Identifiers

PMID36503889
PMCPMC9795852
OpenAlexW4310018873

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.