ArticleAnimal microbiome2022
The skin microbiota of the axolotl Ambystoma altamirani is highly influenced by metamorphosis and seasonality but not by pathogen infection.
Article in Animal microbiome, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Exploring the ecological drivers of bacteriophage diversity and functional viral potential in the skin of the axolotl Ambystoma altamirani.FEMS microbiology ecology · 2026Article
- Genome-Wide Analysis of an Endangered Axolotl Endemic to Mexico Reveals Genomic Variation Associated with Body Condition, Environment, and Infection by a Pathogenic Fungus.Genome biology and evolution · 2026Article
- Identification of Opportunistic Pathogens on the Skin of Salamanders for Use as Molecular Targets of a De Novo Design of Multitarget Anti-International journal of microbiology · 2026Article
- Differences in composition and potential function of the bacterial communities of cave- and surface-dwelling Mexican salamanders.Animal microbiome · 2025Article
- More Than Meets the Eye: Unraveling the Interactions Between Skin Microbiota and Habitat in an Opportunistic Amphibian.Microbial ecology · 2025Article
- The impact of microbiome diversity and composition on host health and susceptibility to disease across amphibian life stages.Frontiers in amphibian and reptile science · 2025Article
- Host Species and Environment Shape the Skin Microbiota of Mexican Axolotls.Microbial ecology · 2024Article
- Skin microbiota during metamorphosis ofFrontiers in microbiology · 2024Article
- Gene functions of theMicrobial genomics · 2024Article
- Host phylogeny and environment shape the diversity of salamander skin bacterial communities.Animal microbiome · 2023Article
- Ontogeny drives shifts in skin bacterial communities in facultatively paedomorphic salamanders.Microbiology (Reading, England) · 2023Article
- The adaptive microbiome hypothesis and immune interactions in amphibian mucus.Developmental and comparative immunology · 2023Review
- Environmental and Anthropogenic Factors Shape the Skin Bacterial Communities of a Semi-Arid Amphibian Species.Microbial ecology · 2023Article
- The skin microbiota of the axolotl Ambystoma altamirani is highly influenced by metamorphosis and seasonality but not by pathogen infection.Animal microbiome · 2022Article
- Temporal microbiome changes in axolotl limb regeneration: Stage-specific restructuring of bacterial and fungal communities with a Flavobacterium bloom during blastema proliferation.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair SocietyArticle
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7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMicrobiomes have been increasingly recognized as major contributors to host health and survival. In amphibians, bacterial members of the skin microbiota protect their hosts by inhibiting the growth of the fungal pathogen Batrachochytrium dendrobatidis (Bd). Even though several studies describe the influence of biotic and abiotic factors over the skin microbiota, it remains unclear how these symbiotic bacterial communities vary across time and development. This is particularly relevant for species that undergo metamorphosis as it has been shown that host physiology and ecology drastically influence diversity of the skin microbiome.
resultsWe found that the skin bacterial communities of the axolotl A. altamirani are largely influenced by the metamorphic status of the host and by seasonal variation of abiotic factors such as temperature, pH, dissolved oxygen and conductivity. Despite high Bd prevalence in these samples, the bacterial diversity of the skin microbiota did not differ between infected and non-infected axolotls, although relative abundance of particular bacteria were correlated with Bd infection intensity.
conclusionsOur work shows that metamorphosis is a crucial process that shapes skin bacterial communities and that axolotls under different developmental stages respond differently to environmental seasonal variations. Moreover, this study greatly contributes to a better understanding of the factors that shape amphibian skin microbiota, especially in a largely underexplored group like axolotls (Mexican Ambystoma species).
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