ArticleBMC infectious diseases2022
Hematologic and inflammatory parameters for determining severity of odontogenic infections at admission: a retrospective study.
Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Neutrophil to lymphocyte ratio in odontogenic infection: a systematic review.Head & face medicine · 2024Pooled it
- Review
- Dynamics of Inflammatory Parameters in Hospitalized and Surgically Treated Patients with Odontogenic Abscesses.Medicina (Kaunas, Lithuania) · 2026Article
- Article
- Beyond Oral Health: Personalized Strategies for Managing Oral Infections in Neutropenic Patients.Journal of personalized medicine · 2026Review
- Diagnostic strategies in necrotizing soft tissue infections: from clinical scores to multi-omics and machine learning.Burns & trauma · 2026Review
- Impact of the COVID-19 Pandemic on Odontogenic Abscess Clinical Patterns and Predictive Factors: A Retrospective Cross-Sectional Study.Journal of clinical medicine · 2025Article
- Involvement of resistant bacteria in the severity of refractory osteonecrosis of the jaw.Clinical oral investigations · 2025Article
- Predictive value of platelet count-related ratios for severity in biliary Escherichia coli and Klebsiella pneumonia bloodstream infections.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025Article
- Predictive factors in difficult postoperative airway management of severe odontogenic deep neck infection.Odontology · 2025Article
- Treatment Behaviors of Patients With Odontogenic Infections During the COVID-19 Pandemic.Cureus · 2025Article
- The Role of qSOFA, Derived Neutrophil-to-Lymphocyte Ratio, MEWS, and PIRO Scores in Predicting the Severity of Odontogenic Infections in Young and Adult Patients.Biomedicines · 2025Article
- The CRP/PAB ratio outperforms the LRINEC score in early diagnosis of Fournier's gangrene.Surgery in practice and science · 2024Article
- Comparative Assessment of the qSOFA, SII, dNLR, and OISS Infection Severity Scores in Diabetic Versus Non-Diabetic Patients with Odontogenic Infections.Biomedicines · 2024Article
- Assessment of Inflammatory Scores in Severity Prediction for Elderly Patients with Odontogenic Infections.Dentistry journal · 2024Article
- Dynamics of Neutrophil-to-Lymphocyte Ratio (NLR), Lymphocyte-to-Monocyte Ratio (LMR), and Platelet-to-Lymphocyte Ratio (PLR) in Patients with Deep Neck Infection.Journal of clinical medicine · 2024Article
- Article
- A Comparative Study of the Aggregate Index of Systemic Inflammation (AISI) and C-Reactive Protein (CRP) in Predicting Odontogenic Abscesses Severity: A Novel Approach to Assessing Immunoinflammatory Response.Diagnostics (Basel, Switzerland) · 2024Article
- When is surgical intervention needed in oral and maxillofacial space infection patients? A retrospective case control study in 46 patients.BMC oral health · 2024Article
- Hospitalisations Due to Dental Infection: A Retrospective Clinical Audit from an Australian Public Hospital.Dentistry journal · 2024Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSevere odontogenic infections in the head and neck region, especially necrotizing soft tissue infection (NSTI) and deep neck abscess, are potentially fatal due to their delayed diagnosis and treatment. Clinically, it is often difficult to distinguish NSTI and deep neck abscess in its early stage from cellulitis, and the decision to perform contrast-enhanced computed tomography imaging for detection is often a challenge. This retrospective case-control study aimed to examine the utility of routine blood tests as an adjunctive diagnostic tool for NSTI in the head and neck region and deep neck abscesses.
methodsPatients with severe odontogenic infections in the head and neck region that required hospitalization were classified into four groups. At admission, hematologic and inflammatory parameters were calculated according to the blood test results. In addition, a decision tree analysis was performed to detect NSTI and deep neck abscesses.
resultsThere were 271 patients, 45.4% in Group I (cellulitis), 22.5% in Group II (cellulitis with shallow abscess formation), 27.3% in Group III (deep neck abscess), and 4.8% in Group IV (NSTI). All hematologic and inflammatory parameters were higher in Groups III and IV. The Laboratory Risk Indicator for Necrotizing Fasciitis score, with a cut-off value of 6 and C-reactive protein (CRP) + the neutrophil-to-lymphocyte ratio (NLR), with a cut-off of 27, were remarkably useful for the exclusion diagnosis for Group IV. The decision tree analysis showed that the systemic immune-inflammation index (SII) of ≥ 282 or < 282 but with a CRP + NLR of ≥ 25 suggests Group III + IV and the classification accuracy was 89.3%.
conclusionsHematologic and inflammatory parameters calculated using routine blood tests can be helpful as an adjunctive diagnostic tool in the early diagnosis of potentially fatal odontogenic infections. An SII of ≥ 282 or < 282 but with a CRP + NLR of ≥ 25 can be useful in the decision-making for performing contrast-enhanced computed tomography imaging.
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