Evidence map›Paper›PMID 36503349›Full record

ReviewNucleus (Austin, Tex.)2022

Aberrant chromatin organization at the nexus of laminopathy disease pathways.

Garrett T Santini, Parisha P Shah, Ashley Karnay, Rajan Jain

Abstract readReview
In one paragraph

Review in Nucleus (Austin, Tex.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Local Non-Coding Regulatory Elements in Muscular Dystrophies.International journal of molecular sciences · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Garrett T SantiniDepartments of Medicine and Cell and Developmental Biology, Penn Cardiovascular Institute, Penn Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA.ORCID 0000-0003-0069-7031
Parisha P ShahDepartments of Medicine and Cell and Developmental Biology, Penn Cardiovascular Institute, Penn Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA.ORCID 0000-0002-7756-6868
Ashley KarnayDepartments of Medicine and Cell and Developmental Biology, Penn Cardiovascular Institute, Penn Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA.ORCID 0000-0001-5907-0124
Rajan JainDepartments of Medicine and Cell and Developmental Biology, Penn Cardiovascular Institute, Penn Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA.ORCID 0000-0002-1979-044X

Funding

NRSA Training CoreTL1TR001880 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI MEAGHER, EMMA ANNE · 2016 to 2025
$10.0M
Single-cell dissection of chromatin architecture mechanisms connecting pathologic instability and transcriptional silencingU01DA052715 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI JAIN, RAJAN, JOYCE, ERIC F. · 2020 to 2024
$3.1M
Deciphering Nuclear Lamina-Chromatin Organization in Cellular Competence and Cardiac DevelopmentDP2HL147123 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI JAIN, RAJAN · 2018 to 2018
$2.4M
Deciphering the Molecular Orchestrators of Heterochromatin-Lamina Interactions at the Nuclear PeripheryF31HL160114 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI KARNAY, ASHLEY · 2021 to 2024
$130k
NCATS NIH HHS TL1 TR001880NHLBI NIH HHS DP2 HL147123NHLBI NIH HHS F31 HL160114NIDA NIH HHS U01 DA052715
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

LaminopathiesLamin Type AChromatinHumansChromatinLamin Type A

Identifiers

PMID36503349
PMCPMC9746625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.