Evidence map›Paper›PMID 36502458›Full record

ArticleEuropean radiology2023

Imaging mismatch between Alberta Stroke Program Early CT Score and perfusion imaging may be a good variable for endovascular treatment.

Pengfei Xing, Xiaowen Zhou, Fang Shen, Yu Zhou, Hongjian Shen, Lei Zhang, Pengfei Yang, Yongwei Zhang, Jianmin Liu

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Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pengfei XingDepartment of Neurovascular Center, Changhai Hospital, Naval Medical University, No.168 Changhai Rd, Shanghai, 200433, China.ORCID http://orcid.org/0000-0002-2663-1092
Xiaowen ZhouDepartment of Neurology, Changzheng Hospital, Naval Medical University, Shanghai, China.
Fang ShenDepartment of Neurovascular Center, Changhai Hospital, Naval Medical University, No.168 Changhai Rd, Shanghai, 200433, China.
Yu ZhouDepartment of Neurovascular Center, Changhai Hospital, Naval Medical University, No.168 Changhai Rd, Shanghai, 200433, China.
Hongjian ShenDepartment of Neurovascular Center, Changhai Hospital, Naval Medical University, No.168 Changhai Rd, Shanghai, 200433, China.
Lei ZhangDepartment of Neurovascular Center, Changhai Hospital, Naval Medical University, No.168 Changhai Rd, Shanghai, 200433, China.
Pengfei YangDepartment of Neurovascular Center, Changhai Hospital, Naval Medical University, No.168 Changhai Rd, Shanghai, 200433, China.
Yongwei ZhangDepartment of Neurovascular Center, Changhai Hospital, Naval Medical University, No.168 Changhai Rd, Shanghai, 200433, China. zhangyongwei@163.com.
Jianmin LiuDepartment of Neurovascular Center, Changhai Hospital, Naval Medical University, No.168 Changhai Rd, Shanghai, 200433, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSome patients with acute large vessel occlusion (LVO) presented imaging mismatch, low Alberta Stroke Program Early CT Score (ASPECTS) with small ischemic core, or high ASPECTS with large ischemic core. The study was designed to explore whether patients with imaging mismatch could benefit from endovascular treatment (EVT).

methodsWe retrospectively reviewed patients with LVO treated with EVT in our center from March 2018 to Jul 2020. Patients were divided into three groups, imaging mismatch, small ischemic core, and large ischemic core groups. Pooled analyses based on stroke onset to treatment time were done. Multivariate regression analysis was performed to explore the factors for good outcomes.

resultsSixty-eight of 419 patients with LVO presented with imaging mismatch, and 35 of those (51%) achieved good outcomes after EVT at 90-day. No significant differences were noted in good outcomes and symptomatic intracranial hemorrhage (sICH) between patients with imaging mismatch and small ischemic core. Compared with large ischemic core, patients with imaging mismatch presented lower risk of sICH (95% confidence interval (CI) 0.04-0.75, p = 0.011) within 6 h and higher proportion of good outcomes (95% CI 0.37-0.82, p = 0.002) at 6 to 24 h. Baseline NIHSS (odds ratio (OR) = 0.91, 95% CI 0.88-0.95)), ASPECTS (OR = 1.14, 95% CI 1.01-1.29), ischemic core (OR = 0.99, 95% CI 0.98-1.00), and sICH (OR = 61.61, 95% CI 8.09-461.32) were associated with good outcomes.

conclusionsPatients with imaging mismatch treated within 24 h could benefit from EVT and without increasing the risk of sICH. KEY POINTS: • Patients with imaging mismatch between ASPECTS and ischemic core could achieve good outcomes after endovascular treatment. • Compared with large ischemic core, patients with imaging mismatch presented lower risk of symptomatic hemorrhage within 6 h and higher proportion of good outcomes within 6-24 h. • Baseline NIHSS score, ASPECTS, ischemic core, and symptomatic intracranial hemorrhage were associated with good outcomes.

Indexed as

Brain IschemiaEndovascular ProceduresStrokeAlbertaHumansIntracranial HemorrhagesPerfusion ImagingRetrospective StudiesThrombectomyTomography, X-Ray ComputedTreatment OutcomeNeuroimagingPerfusionStrokeThrombectomyTomography

Identifiers

PMID36502458

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.