Evidence map›Paper›PMID 36501324›Full record

ArticlePlants (Basel, Switzerland)2022

Anticholinesterase Activity of Budmunchiamine Alkaloids Revealed by Comparative Chemical Profiling of Two

Mai E Hussein, Osama G Mohamed, Ahlam M El-Fishawy, Hesham I El-Askary, Ahmed A Hamed, Marwa M Abdel-Aziz, Radwan Alnajjar, Amany Belal, Ahmed M Naglah, Abdulrahman A Almehizia and 3 more

Open access · goldAbstract read
In one paragraph

Article in Plants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  4. Cognitive-enhancing effect ofRSC advances · 2024
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  11. Article
  12. Cholinesterase Inhibitors from an Endophytic FungusMolecules (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 5 countries.

Mai E HusseinPharmacognosy Department, Faculty of Pharmacy, Cairo University, Kasr el Aini St., Cairo 11562, Egypt.ORCID 0000-0002-8838-8147
Osama G MohamedPharmacognosy Department, Faculty of Pharmacy, Cairo University, Kasr el Aini St., Cairo 11562, Egypt.ORCID 0000-0003-3216-6948
Ahlam M El-FishawyPharmacognosy Department, Faculty of Pharmacy, Cairo University, Kasr el Aini St., Cairo 11562, Egypt.
Hesham I El-AskaryPharmacognosy Department, Faculty of Pharmacy, Cairo University, Kasr el Aini St., Cairo 11562, Egypt.
Ahmed A HamedMicrobial Chemistry Department, National Research Centre, 33 El-Buhouth Street, Dokki, Giza 12622, Egypt.ORCID 0000-0002-9997-9284
Marwa M Abdel-AzizRegional Center for Mycology and Biotechnology (RCMB), Al-Azhar University, Cairo 11651, Egypt.
Radwan AlnajjarDepartment of Chemistry, Faculty of Science, University of Benghazi, Benghazi 16063, Libya.ORCID 0000-0003-1869-9596
Amany BelalMedicinal Chemistry Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514, Egypt.ORCID 0000-0003-1045-0163
Ahmed M NaglahDrug Exploration and Development Chair (DEDC), Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0003-4377-5239
Abdulrahman A AlmehiziaDrug Exploration and Development Chair (DEDC), Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0001-8711-3873
Ahmed A Al-KarmalawyPharmaceutical Chemistry Department, Faculty of Pharmacy, Ahram Canadian University, 6th of October City, Giza 12566, Egypt.ORCID 0000-0002-8173-6073
Ashootosh TripathiNatural Products Discovery Core, Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0003-2297-8088
Amira S El SenousyPharmacognosy Department, Faculty of Pharmacy, Cairo University, Kasr el Aini St., Cairo 11562, Egypt.
Cairo University · EGKing Saud University · SAAhram Canadian University · EGAl-Azhar University · EGBeni-Suef University · EGNational Research Centre · EGUniversity of Cape Town · ZAUniversity of Michigan · US

Funding

King Saud University; Vice Deanship of Scientific Research Chairs; Drug Exploration and Development Chair 00 00
6 · The paper itself

Abstract

Alzheimer's disease remains a global health challenge and an unmet need requiring innovative approaches to discover new drugs. The current study aimed to investigate the inhibitory activity of

Indexed as

A. lucidioranticholinesteraseA. procerabudmunchiamineMM-GBSAmolecular dockingmolecular networkingUHPLC–QTOF

Identifiers

PMID36501324
PMCPMC9738009
OpenAlexW4310380212

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.