Evidence map›Paper›PMID 36501225›Full record

ArticleNutrients2022

Effect of Inulin Intervention on Metabolic Control and Methylation of

Ollin Celeste Martínez-Ramírez, Azucena Salazar-Piña, Ximena Cerón-Ramírez, Julieta Rubio-Lightbourn, Fernando Torres-Romero, Leonora Casas-Avila, Clementina Castro-Hernández

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Ollin Celeste Martínez-RamírezFacultad de Nutrición, Universidad Autónoma del Estado de Morelos, Cuernavaca C.P. 62350, Morelos, Mexico.ORCID 0000-0002-1177-5261
Azucena Salazar-PiñaFacultad de Nutrición, Universidad Autónoma del Estado de Morelos, Cuernavaca C.P. 62350, Morelos, Mexico.ORCID 0000-0003-0800-7226
Ximena Cerón-RamírezFacultad de Nutrición, Universidad Autónoma del Estado de Morelos, Cuernavaca C.P. 62350, Morelos, Mexico.
Julieta Rubio-LightbournDepartamento de Medicina Genómica y Toxicología Ambiental, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad de México C.P. 04510, Mexico.
Fernando Torres-RomeroFacultad de Nutrición, Universidad Autónoma del Estado de Morelos, Cuernavaca C.P. 62350, Morelos, Mexico.
Leonora Casas-AvilaLaboratorio de Medicina Genómica, Instituto Nacional de Rehabilitación, Ciudad de Mexico C.P. 14389, Mexico.
Clementina Castro-HernándezUnidad de Investigación Biomédica en Cáncer, Instituto Nacional de Cancerología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad de México C.P. 14080, Mexico.ORCID 0000-0002-5641-3627
Universidad Autónoma del Estado de Morelos · MXInstituto Nacional de Cancerología · MXInstituto Nacional de Rehabilitación · MXUniversidad Nacional Autónoma de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsCurrently, treatments are being sought to improve the control of type II diabetes mellitus (T2DM), and inulin has been shown to be effective in reducing glucose levels and other metabolic control parameters. These effects on metabolic control may be associated with changes in the epigenetic modulation of genes of the insulin pathway. Therefore, our objective is to determine the effect of agave inulin in metabolic control parameters and in

methodsThis was a longitudinal experimental study with 67 Mexican participants who received an intervention of inulin agave (10 g daily) for 2 months. The methylation of the

resultsFor the

conclusionFor the first time, we report the modification in the methylation of two genes,

Indexed as

Diabetes Mellitus, Type 2HumansInsulinInsulin Receptor Substrate ProteinsInulinMethylationMexicoInsulinInsulin Receptor Substrate ProteinsInulinIRS1 protein, humanagave inulinepigeneticsINSIRS1T2DM

Identifiers

PMID36501225
PMCPMC9737482
OpenAlexW4311667079

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.