ReviewNutrients2022
Resveratrol and SIRT1: Antiaging Cornerstones for Oocytes?
Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 27 citations in OpenAlex.
- Effect of Resveratrol on Markers of Oxidative Stress and Sirtuin 1 in Elderly Adults with Type 2 Diabetes.International journal of molecular sciences · 2023Trial
- Restoring NAD⁺-Sirtuins Signaling: A Novel Approach to Combat Male Reproductive Aging.The world journal of men's health · 2026Review
- Enhancing the Oocyte Ultrastructure and Antioxidant Defence System of In Vitro Matured Buffalo Oocytes via Resveratrol Supplementation.Reproduction in domestic animals = Zuchthygiene · 2026Article
- The role of mTOR signaling in regulating the quality of mammalian oocytes.Journal of assisted reproduction and genetics · 2026Review
- Resveratrol supplementation mitigates age-related declines in egg production, quality, and ovarian health of laying hens.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- Nutritional Regulation of Ovarian Bioenergetics: Implications for Reproductive Aging and Female Infertility.Nutrients · 2026Review
- Effects of Vitamin C, Rosmarinic Acid, or Quercetin on Fertilisation-Related Gene Expression in Porcine Cumulus-Oocyte Complexes During In Vitro Maturation.International journal of molecular sciences · 2026Article
- Synthesis and evaluation of resveratrol-cerium modified hydroxyapatite for enhanced bone repair scaffolds.RSC advances · 2026Article
- Oxidative Stress andInternational journal of molecular sciences · 2026Review
- Influence of Certain Natural Bioactive Compounds on Glycemic Control: A Narrative Review.Nutrients · 2025Review
- Research Progress on the Interaction Between SIRT1 and Mitochondrial Biochemistry in the Aging of the Reproductive System.Biology · 2025Review
- The role of Chinese herbal medicine in diminished ovarian reserve management.Journal of ovarian research · 2025Review
- The hippo pathway: a molecular bridge between environmental cues and pace of life.BMC ecology and evolution · 2025Review
- Resveratrol modulates phosphorylation of ERK and AKT in murine cementoblasts during in vitro orthodontic compression.BMC oral health · 2025Article
- Telomeres and SIRT1 as Biomarkers of Gamete Oxidative Stress, Fertility, and Potential IVF Outcome.International journal of molecular sciences · 2024Review
- Interplay among Oxidative Stress, Autophagy, and the Endocannabinoid System in Neurodegenerative Diseases: Role of the Nrf2- p62/SQSTM1 Pathway and Nutraceutical Activation.Current issues in molecular biology · 2024Review
- Ovarian aging: energy metabolism of oocytes.Journal of ovarian research · 2024Review
- Assessing the Influence of Maternal Age in Bovine Embryos and Oocytes: A Model for Human Reproductive Aging.Aging and disease · 2024Review
- T helper cell 17/regulatory T cell balance regulates ulcerative colitis and the therapeutic role of natural plant components: a review.Frontiers in medicine · 2024Review
- Editorial: Stem cell exhaustion in aging.Frontiers in aging · 2024Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is well-known that there is an enormous variability in the aging-related decline of oocytes' quantity and their developmental competence among mammalian species. The implication of female germline aging is profound from the perspective of evolutionary conservation of the aging mechanism, a topic of continuous and widespread interest that has yet to be fully addressed for the mammalian oocyte. There is a certain need to develop novel antiaging strategies to delay or slow down aging, or even to reverse the aging phenotype in the oocyte. In the past two decades, several antioxidants have been tested for this purpose. Resveratrol is one of these latter-mentioned compounds, which has shown anti-inflammatory and antiaging properties in a dose-dependent manner. Interestingly, resveratrol appears to enhance the activity of so-called Sirtuin 1, too. Therefore, the aim of this review is to summarize and discuss the latest findings related to resveratrol, Sirtuin 1, and their crosstalk and influence on the mammalian oocyte to elucidate the question of whether these factors can delay or slow down reproductive aging.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.