Evidence map›Paper›PMID 36501085›Full record

ArticleNutrients2022

Antileukemic, Antioxidant, Anti-Inflammatory and Healing Activities Induced by a Polyphenol-Enriched Fraction Extracted from Leaves of

Hamza Mechchate, Carlos Eduardo de Castro Alves, Imane Es-Safi, Amal Amaghnouje, Fatima Zahra Jawhari, Regiane Costa de Oliveira, Alice de Freitas Gomes, Raffaele Conte, Gemilson Soares Pontes, Dalila Bousta and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hamza MechchateLaboratory of Biotechnology, Environment, Agrifood, and Health, University of Sidi Mohamed Ben Abdellah (USMBA), Fez B.P. 1796, Morocco.ORCID 0000-0003-4571-9089
Carlos Eduardo de Castro AlvesPost-Graduate Program in Basic and Applied Immunology, Institute of Biological Sciences, Federal University of Amazonas, Manaus 69077-000, AM, Brazil.
Imane Es-SafiLaboratory of Biotechnology, Environment, Agrifood, and Health, University of Sidi Mohamed Ben Abdellah (USMBA), Fez B.P. 1796, Morocco.
Amal AmaghnoujeLaboratory of Biotechnology, Environment, Agrifood, and Health, University of Sidi Mohamed Ben Abdellah (USMBA), Fez B.P. 1796, Morocco.ORCID 0000-0002-4759-3312
Fatima Zahra JawhariLaboratory of Biotechnology, Environment, Agrifood, and Health, University of Sidi Mohamed Ben Abdellah (USMBA), Fez B.P. 1796, Morocco.ORCID 0000-0003-1622-4490
Regiane Costa de OliveiraPost-Graduate Program in Hematology, The State University of Amazonas, Foundation of Hematology and Hemotherapy of Amazonas, Manaus 69050-010, AM, Brazil.ORCID 0000-0003-0319-785X
Alice de Freitas GomesPost-Graduate Program in Hematology, The State University of Amazonas, Foundation of Hematology and Hemotherapy of Amazonas, Manaus 69050-010, AM, Brazil.
Raffaele ConteResearch Institute on Terrestrial Ecosystems (IRET)-CNR, Via Pietro Castellino 111, 80131 Naples, Italy.ORCID 0000-0002-6266-4991
Gemilson Soares PontesPost-Graduate Program in Basic and Applied Immunology, Institute of Biological Sciences, Federal University of Amazonas, Manaus 69077-000, AM, Brazil.ORCID 0000-0001-9001-7954
Dalila BoustaLaboratory of Biotechnology, Environment, Agrifood, and Health, University of Sidi Mohamed Ben Abdellah (USMBA), Fez B.P. 1796, Morocco.
Andriy GrafovMaterials Chemistry Division, Department of Chemistry, University of Helsinki, A.I. Virtasen aukio 1, 00560 Helsinki, Finland.ORCID 0000-0002-7387-3676

Funding

European Commission Horizon 2020 MSCA-RISE-2016-734759, acronym VAHVISTUS
6 · The paper itself

Abstract

Natural products have offered a number of exciting approaches in cancer treatment over the years. In this study, we investigated the prophylactic and therapeutic effects of the polyphenol-enriched fraction extracted from

Indexed as

LeukemiaMyrtusAnimalsAnti-Inflammatory AgentsAntioxidantsMicePlant ExtractsPlant LeavesPolyphenolsAnti-Inflammatory AgentsAntioxidantsPlant ExtractsPolyphenolsacute toxicity studyanticancerbeta carotene bleaching testcarrageenan-induced edema testferric reducing antioxidant powerhemolysis testHL60K562total antioxidant capacitywound healing activity

Identifiers

PMID36501085
PMCPMC9740279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.