Evidence map›Paper›PMID 36501064›Full record

ArticleNutrients2022

Early Enteral Feeding of the Preterm Infant-Delay until Own Mother's Breastmilk Becomes Available? (Israel, 2012-2017).

Noa Ofek Shlomai, Yonatan Shneor Patt, Yaara Wazana, Tomer Ziv-Baran, Tzipora Strauss, Iris Morag

Abstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Noa Ofek ShlomaiDepartment of Neonatology, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 9190501, Israel.ORCID 0000-0001-5004-2397
Yonatan Shneor PattSackler Faculty of Medicine, Tel Aviv University, Tel-Aviv 6997801, Israel.ORCID 0000-0002-0412-1729
Yaara WazanaSackler Faculty of Medicine, Tel Aviv University, Tel-Aviv 6997801, Israel.
Tomer Ziv-BaranDepartment of Epidemiology and Preventive Medicine, School of Public Health, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 6997801, Israel.ORCID 0000-0002-2589-8473
Tzipora StraussSackler Faculty of Medicine, Tel Aviv University, Tel-Aviv 6997801, Israel.
Iris MoragSackler Faculty of Medicine, Tel Aviv University, Tel-Aviv 6997801, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo consider the question of whether to initiate trophic feeds with formula in the absence of own mother's breastmilk or to wait for breastmilk to be available.

methodsA retrospective study of infants born prior to 32 weeks of gestation during the period 2012-2017 at a single tertiary center in Tel Aviv, Israel. Three TF groups were defined: exclusive breastmilk, mixed, and exclusive formula. Univariate and multivariate analyses were conducted. Logistic regression was used, and adjusted odds ratio and 95% interval were reported.

resultsUnivariate analysis demonstrated that infants in the exclusive breastmilk group were born earlier, had lower birth weights and lower Apgar scores, were given lower volumes of TF, and were more likely to have a longer hospital stay. Poor composite outcome was more common among the exclusive breastmilk group. Multivariate regression analysis revealed no differences in incidence of early neonatal morbidities between the groups, except for longer duration of parenteral nutrition in the exclusive breastmilk group.

conclusionIn our cohort, exclusive formula TF was not associated with increased risk of any of the studied morbidities. Clinicians should consider this finding in deciding between early TF or fasting while waiting for own mother's breastmilk.

Indexed as

Infant, Newborn, DiseasesInfant, PrematureFemaleHumansInfantInfant FormulaInfant, NewbornInfant, Very Low Birth WeightMilk, HumanMothersRetrospective Studiesbreastmilkformula feedingtrophic feedingvery low birth weight

Identifiers

PMID36501064
PMCPMC9738232

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.