SynthesisNutrients2022
Dietary Intake and Diabetic Retinopathy: A Systematic Review of the Literature.
Synthesis in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Mediterranean diet and diabetic microvascular complications: a systematic review and meta-analysis.BMC nutrition · 2025Pooled it
- Blood omega-3 biomarkers, diabetic retinopathy and retinal vessel status in patients with type 1 diabetes.Eye (London, England) · 2025Trial
- Effects of diabetes complications on body composition, dietary intake, and metabolic parameters.Acta diabetologica · 2026Article
- Dietary patterns and exploratory gut microbiota profiles associated with diabetic retinopathy and cognitive impairment in type 2 diabetes.Nutrition & metabolism · 2026Article
- Healthy Dietary Patterns and Risk of Major Eye Diseases: Evidence From Nationally Population-Based Data and Bibliometric Analysis.Food science & nutrition · 2026Article
- Diabetic retinopathy: why some eyes suffer more - a focus on retina-specific risk factors and metabolic memory.Journal of translational medicine · 2026Review
- Recent Investigations on Pathogenesis, Biomarkers, Epigenetics, and Emerging Therapeutic Strategies to Modulate Multiple Signaling Pathways in Diabetic Retinopathy.Journal of ophthalmology · 2026Review
- Association Between Serum Vitamin D3 Levels and Diabetic Macular Edema in Patients with Type 2 Diabetes: A Retrospective Case-Control Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Association between nutritional‑inflammatory status and diabetic retinopathy in adults with diabetes: insights from a US population‑based survey and a Chinese hospital‑based clinical cohort.Frontiers in endocrinology · 2026Article
- Effect of a behaviour change wheel nursing program on glycaemic control, self-efficacy, and hospitalisation outcomes in patients with diabetic retinopathy.Scientific reports · 2025Article
- Pathophysiological Role and Therapeutic Potential of Vitamin C in Metabolic Syndrome and Type 2 Diabetes Mellitus.Metabolites · 2025Review
- Effects of physical activity on visual outcomes among type 2 diabetes patients: protocol for a scoping review of randomized controlled trials.Systematic reviews · 2025Article
- Natural remedies proposed for the management of diabetic retinopathy (DR): diabetic complications.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- Causal effect of the 25-Hydroxyvitamin D concentration on ocular diseases: A Mendelian randomization study.Scientific reports · 2025Article
- Sex differences in the impact of controlling nutritional status score on diabetic retinopathy: findings of 2003-2018 National Health and Nutrition Examination Survey.Frontiers in nutrition · 2025Article
- The application of procyanidins in diabetes and its complications: a review of preclinical studies.Frontiers in pharmacology · 2025Review
- Risk factors for diabetic retinopathy in young and middle-aged patients: a retrospective study.BMC ophthalmology · 2024Article
- Deciphering the role of oleic acid in diabetic retinopathy: an empirical analysis of monounsaturated fatty acids.Nutrition & metabolism · 2024Article
- Effect of the Mediterranean Diet (MeDi) on the Progression of Retinal Disease: A Narrative Review.Nutrients · 2024Review
- Management of Microcomplications of Diabetes Mellitus: Challenges, Current Trends, and Future Perspectives in Treatment.Biomedicines · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Diabetic retinopathy (DR) is a common microvascular complication of diabetes mellitus. The evidence connecting dietary intake and DR is emerging, but uncertain. We conducted a systematic review to comprehensively summarize the current understanding of the associations between dietary consumption, DR and diabetic macular edema (DME). We systematically searched PubMed, Embase, Medline, and the Cochrane Central Register of Controlled Trials between January 1967 to May 2022 for all studies investigating the effect of diet on DR and DME. Of the 4962 articles initially identified, 54 relevant articles were retained. Our review found that higher intakes of fruits, vegetables, dietary fibers, fish, a Mediterranean diet, oleic acid, and tea were found to have a protective effect against DR. Conversely, high intakes of diet soda, caloric intake, rice, and choline were associated with a higher risk of DR. No association was seen between vitamin C, riboflavin, vitamin D, and milk and DR. Only one study in our review assessed dietary intake and DME and found a risk of high sodium intake for DME progression. Therefore, the general recommendation for nutritional counseling to manage diabetes may be beneficial to prevent DR risk, but prospective studies in diverse diabetic populations are needed to confirm our findings and expand clinical guidelines for DR management.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.