Evidence map›Paper›PMID 36500852›Full record

ArticleNanomaterials (Basel, Switzerland)2022

Laser-Induced µ-Rooms for Osteocytes on Implant Surface: An In Vivo Study.

Vadim Veiko, Yuliya Karlagina, Ekaterina Zernitckaia, Elena Egorova, Maxim Radaev, Andrey Yaremenko, Gennadiy Chernenko, Valery Romanov, Nadezhda Shchedrina, Elena Ivanova and 2 more

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Vadim VeikoInstitute of Laser Technologies, ITMO University, Saint-Petersburg 197101, Russia.ORCID 0000-0001-6071-3449
Yuliya KarlaginaInstitute of Laser Technologies, ITMO University, Saint-Petersburg 197101, Russia.ORCID 0000-0002-6927-9551
Ekaterina ZernitckaiaDepartment of Dental Surgery and Maxillofacial Surgery, Pavlov First Saint-Petersburg State Medical University, Saint-Petersburg 197022, Russia.ORCID 0000-0002-3819-693X
Elena EgorovaInstitute of Laser Technologies, ITMO University, Saint-Petersburg 197101, Russia.ORCID 0000-0002-1461-0673
Maxim RadaevInstitute of Laser Technologies, ITMO University, Saint-Petersburg 197101, Russia.ORCID 0000-0003-3891-0280
Andrey YaremenkoDepartment of Dental Surgery and Maxillofacial Surgery, Pavlov First Saint-Petersburg State Medical University, Saint-Petersburg 197022, Russia.ORCID 0000-0002-7700-7724
Gennadiy ChernenkoLenmiriot Dental Implant Prosthetics Manufacture, Saint-Petersburg 193079, Russia.
Valery RomanovInstitute of Laser Technologies, ITMO University, Saint-Petersburg 197101, Russia.ORCID 0000-0003-1468-9438
Nadezhda ShchedrinaInstitute of Laser Technologies, ITMO University, Saint-Petersburg 197101, Russia.ORCID 0000-0002-1517-1043
Elena IvanovaSTEM, School of Science, RMIT University, Melbourne 3000, Australia.ORCID 0000-0002-5509-8071
Boris ChichkovInstitute of Quantum Optics, Leibniz University of Hanover, 30167 Hannover, Germany.ORCID 0000-0002-8129-7373
Galina OdintsovaInstitute of Laser Technologies, ITMO University, Saint-Petersburg 197101, Russia.ORCID 0000-0001-9581-4290
ITMO University · RUFirst Pavlov State Medical University of St. Petersburg · RULeibniz University Hannover · DERMIT University · AU

Funding

Ministry of Science and Higher Education of the Russian Federation 075-11-2021-045 of 24.06.2021
6 · The paper itself

Abstract

Laser processing of dental implant surfaces is becoming a more widespread replacement for classical techniques due to its undeniable advantages, including control of oxide formation and structure and surface relief at the microscale. Thus, using a laser, we created several biomimetic topographies of various shapes on the surface of titanium screw-shaped implants to research their success and survival rates. A distinctive feature of the topographies is the presence of "µ-rooms", which are special spaces created by the depressions and elevations and are analogous to the µ-sized room in which the osteocyte will potentially live. We conducted the comparable in vivo study using dental implants with continuous (G-topography with µ-canals), discrete (S-topography with μ-cavities), and irregular (I-topography) laser-induced topographies. A histological analysis performed with the statistical method (with p-value less than 0.05) was conducted, which showed that G-topography had the highest BIC parameter and contained the highest number of mature osteocytes, indicating the best secondary stability and osseointegration.

Indexed as

biocompatibilityin vivolaser texturingosseointegrationrabbit tibiatitanium implantstopography

Identifiers

PMID36500852
PMCPMC9737095
OpenAlexW4310074536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.