Evidence map›Paper›PMID 36500547›Full record

ArticleMolecules (Basel, Switzerland)2022

Identification of Novel Antifungal Skeleton of Hydroxyethyl Naphthalimides with Synergistic Potential for Chemical and Dynamic Treatments.

Pengli Zhang, Vijai Kumar Reddy Tangadanchu, Chenghe Zhou

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Pengli ZhangInstitute of Bioorganic & Medicinal Chemistry, Key Laboratory of Applied Chemistry of Chongqing Municipality, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.
Vijai Kumar Reddy TangadanchuDepartment of Radiology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA.ORCID 0000-0003-4073-5362
Chenghe ZhouInstitute of Bioorganic & Medicinal Chemistry, Key Laboratory of Applied Chemistry of Chongqing Municipality, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.
Southwest University · CNWashington University in St. Louis · US

Funding

Chongqing Special Foundation for Postdoctoral Research Proposa Xm2016039National Natural Science Foundation of China 21971212the Key Project of Innovation Research 2035 Pilot Plan of Southwest University SWU-XDZD22007
6 · The paper itself

Abstract

The invasion of pathogenic fungi poses nonnegligible threats to the human health and agricultural industry. This work exploited a family of hydroxyethyl naphthalimides as novel antifungal species with synergistic potential of chemical and dynamic treatment to combat the fungal resistance. These prepared naphthalimides showed better antifungal potency than fluconazole towards some tested fungi including

Indexed as

Drug Resistance, FungalNaphthalimidesAntifungal AgentsFluconazoleHumansMicrobial Sensitivity TestsProspective StudiesAntifungal AgentsFluconazoleNaphthalimidesantifungalmembranenaphthalimidereactive oxygen species

Identifiers

PMID36500547
PMCPMC9739515
OpenAlexW4311530351

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.