Evidence map›Paper›PMID 36500529›Full record

ReviewMolecules (Basel, Switzerland)2022

Azumamides A-E: Isolation, Synthesis, Biological Activity, and Structure-Activity Relationship.

Sooheum Jo, Jin-Hee Kim, Jiyeon Lee, Youngjun Park, Jaebong Jang

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Sooheum JoCollege of Pharmacy, Korea University, Sejong 30019, Republic of Korea.
Jin-Hee KimCollege of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon 21983, Republic of Korea.
Jiyeon LeeCollege of Pharmacy, Korea University, Sejong 30019, Republic of Korea.
Youngjun ParkLaboratory of Immune and Inflammatory Disease, Jeju Research Institute of Pharmaceutical Sciences, College of Pharmacy, Jeju National University, Jeju 63243, Republic of Korea.
Jaebong JangCollege of Pharmacy, Korea University, Sejong 30019, Republic of Korea.ORCID 0000-0002-7962-3395
Korea University · KRJeju National University · KRYonsei University · KR

Funding

National Research Foundation of Korea 2021R1C1C1009438National Research Foundation of Korea 2021R1C1C1010526National Research Foundation of Korea NRF-2018R1A6A1A03023718
6 · The paper itself

Abstract

Cyclic peptides are one of the important chemical groups in the HDAC inhibitor family. Following the success of romidepsin in the clinic, naturally occurring cyclic peptides with a hydrophilic moiety have been intensively studied to test their function as HDAC inhibitors. Azumamides A-E, isolated from

Indexed as

Histone Deacetylase InhibitorsPeptides, CyclicAmino AcidsHydrophobic and Hydrophilic InteractionsStructure-Activity RelationshipAmino AcidsHistone Deacetylase InhibitorsPeptides, Cyclicasymmetric synthesisazumamideHDAC inhibitormacrocyclizationnaturally occurring cyclic peptideβ-amino acid

Identifiers

PMID36500529
PMCPMC9737774
OpenAlexW4311530269

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.