Evidence map›Paper›PMID 36500517›Full record

ArticleMolecules (Basel, Switzerland)2022

X-ray Structures and Computational Studies of Two Bioactive 2-(Adamantane-1-carbonyl)-

Lamya H Al-Wahaibi, Kowsalya Alagappan, Olivier Blacque, Ahmed A B Mohamed, Hanan M Hassan, María Judith Percino, Ali A El-Emam, Subbiah Thamotharan

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lamya H Al-WahaibiDepartment of Chemistry, College of Sciences, Princess Nourah Bint Abdulrahman University, Riyadh 11671, Saudi Arabia.
Kowsalya AlagappanBiomolecular Crystallography Laboratory, Department of Bioinformatics, School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur 613 401, India.
Olivier BlacqueDepartment of Chemistry, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
Ahmed A B MohamedDepartment of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.ORCID 0000-0003-3912-1021
Hanan M HassanDepartment of Pharmacology and Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, International Costal Road, Gamasa City, Mansoura 11152, Egypt.
María Judith PercinoUnidad de Polímeros y Electrónica Orgánica, Instituto de Ciencias, Benemérita Universidad Autónoma de Puebla, Val3-Ecocampus Valsequillo, Independencia O2 Sur 50, San Pedro Zacachimalpa, Puebla 72960, Mexico.ORCID 0000-0003-1610-7155
Ali A El-EmamDepartment of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.ORCID 0000-0002-9325-9497
Subbiah ThamotharanBiomolecular Crystallography Laboratory, Department of Bioinformatics, School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur 613 401, India.ORCID 0000-0003-2758-6649

Funding

Princess Nourah bint Abdulrahman University PNURSP2022R3
6 · The paper itself

Abstract

Two biologically active adamantane-linked hydrazine-1-carbothioamide derivatives, namely 2-(adamantane-1-carbonyl)-

Indexed as

AdamantaneCrystallography, X-RayHydrazinesHydrogen BondingMolecular Docking SimulationUreaseX-RaysAdamantanehydrazineHydrazinesUreaseadamantaneantiproliferative agentsCLP–PixelH-H bondingHirshfeld surfacehydrazine-1-carbothioamidemolecular dockingQTAIMurease inhibition

Identifiers

PMID36500517
PMCPMC9741201

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.