Evidence map›Paper›PMID 36500459›Full record

ReviewMolecules (Basel, Switzerland)2022

Role of Phenylpropanoids and Flavonoids in Plant Resistance to Pests and Diseases.

Marie-Louisa Ramaroson, Claude Koutouan, Jean-Jacques Helesbeux, Valérie Le Clerc, Latifa Hamama, Emmanuel Geoffriau, Mathilde Briard

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 152 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
152citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

152 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Natural Pigments and Cyclodextrins: Overview on a Synergistic Approach to Encapsulation.Comprehensive reviews in food science and food safety · 2026
    Review
  5. Article
  6. TheHorticulture research · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. PlantInternational journal of molecular sciences · 2026
    Review
  12. Microwave and solvent extraction ofFood chemistry: X · 2026
    Article
  13. Article
  14. Article
  15. Plants (Basel, Switzerland) · 2026
    Article
  16. Review
  17. Review
  18. Article
  19. Phytochemical Diversity inPlants (Basel, Switzerland) · 2026
    Article
  20. FlavonoidInternational journal of molecular sciences · 2026
    Article

92 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marie-Louisa RamarosonUniv Angers, Institut Agro, INRAE, IRHS, SFR 4207 QUASAV, F-49000 Angers, France.ORCID 0000-0003-0206-4369
Claude KoutouanUniv Angers, Institut Agro, INRAE, IRHS, SFR 4207 QUASAV, F-49000 Angers, France.
Jean-Jacques HelesbeuxUniv Angers, SONAS, SFR 4207 QUASAV, F-49000 Angers, France.ORCID 0000-0002-1894-8911
Valérie Le ClercUniv Angers, Institut Agro, INRAE, IRHS, SFR 4207 QUASAV, F-49000 Angers, France.ORCID 0000-0002-0935-2876
Latifa HamamaUniv Angers, Institut Agro, INRAE, IRHS, SFR 4207 QUASAV, F-49000 Angers, France.
Emmanuel GeoffriauUniv Angers, Institut Agro, INRAE, IRHS, SFR 4207 QUASAV, F-49000 Angers, France.
Mathilde BriardUniv Angers, Institut Agro, INRAE, IRHS, SFR 4207 QUASAV, F-49000 Angers, France.ORCID 0000-0002-4952-2462

Funding

Ministère de l'Enseignement Supérieur et de la Recherche and the RFI "Objectif Végétal of the Pays de la Loire" Flarescad
6 · The paper itself

Abstract

Phenylpropanoids and flavonoids are specialized metabolites frequently reported as involved in plant defense to biotic or abiotic stresses. Their biosynthetic accumulation may be constitutive and/or induced in response to external stimuli. They may participate in plant signaling driving plant defense responses, act as a physical or chemical barrier to prevent invasion, or as a direct toxic weapon against microbial or insect targets. Their protective action is described as the combinatory effect of their localization during the host's interaction with aggressors, their sustained availability, and the predominance of specific compounds or synergy with others. Their biosynthesis and regulation are partly deciphered; however, a lot of gaps in knowledge remain to be filled. Their mode of action on microorganisms and insects probably arises from an interference with important cellular machineries and structures, yet this is not fully understood for all type of pests and pathogens. We present here an overview of advances in the state of the art for both phenylpropanoids and flavonoids with the objective of paving the way for plant breeders looking for natural sources of resistance to improve plant varieties. Examples are provided for all types of microorganisms and insects that are targeted in crop protection. For this purpose, fields of phytopathology, phytochemistry, and human health were explored.

Indexed as

FlavonoidsPlantsAnimalsHumansInsectaPlant DiseasesStress, PhysiologicalFlavonoidsbiotic stressplant defenseresistance mechanismsspecialized metabolites

Identifiers

PMID36500459
PMCPMC9735708

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.