Evidence map›Paper›PMID 36500442›Full record

ReviewMolecules (Basel, Switzerland)2022

Novel Production Methods of Polyhydroxyalkanoates and Their Innovative Uses in Biomedicine and Industry.

Guillermo Fernandez-Bunster, Pamela Pavez

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Polyhydroxyalkanoate Copolymer Production by RecombinantBioengineering (Basel, Switzerland) · 2024
    Article
  9. Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Guillermo Fernandez-BunsterSchool of Medical Technology, Faculty of Medicine, University of Valparaiso, Campus San Felipe, Camino la Troya S/N & El Convento, Circunvalación Ote, San Felipe 2173310, Chile.ORCID 0000-0001-9433-5204
Pamela PavezSchool of Biological and Chemical Sciences, Faculty of Medicine and Science, San Sebastian University, Santiago 8420524, Chile.
San Sebastián University · CLUniversidad de Aconcagua · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyhydroxyalkanoate (PHA), a biodegradable polymer obtained from microorganisms and plants, have been widely used in biomedical applications and devices, such as sutures, cardiac valves, bone scaffold, and drug delivery of compounds with pharmaceutical interests, as well as in food packaging. This review focuses on the use of polyhydroxyalkanoates beyond the most common uses, aiming to inform about the potential uses of the biopolymer as a biosensor, cosmetics, drug delivery, flame retardancy, and electrospinning, among other interesting uses. The novel applications are based on the production and composition of the polymer, which can be modified by genetic engineering, a semi-synthetic approach, by changing feeding carbon sources and/or supplement addition, among others. The future of PHA is promising, and despite its production costs being higher than petroleum-based plastics, tools given by synthetic biology, bioinformatics, and machine learning, among others, have allowed for great production yields, monomer and polymer functionalization, stability, and versatility, a key feature to increase the uses of this interesting family of polymers.

Indexed as

PetroleumPolyhydroxyalkanoatesBiopolymersDrug Delivery SystemsFood PackagingBiopolymersPetroleumPolyhydroxyalkanoatesbacterial accumulationbiodegradable polymersbiotechnologyindustrypolyhydroxyalkanoaterenewable polymers

Identifiers

PMID36500442
PMCPMC9740486
OpenAlexW4310382639

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.