Exploration of Anti-HIV Phytocompounds against SARS-CoV-2 Main Protease: Structure-Based Screening, Molecular Simulation, ADME Analysis and Conceptual DFT Studies.
Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
19 authors at 9 institutions in 7 countries.
Mahadevamurthy MuraliDepartment of Studies in Botany, University of Mysore, Mysore 570006, India.ORCID 0000-0003-2284-344X
Hittanahallikoppal Gajendramurthy GowthamDepartment of PG Studies in Biotechnology, Nrupathunga University, Nrupathunga Road, Bangalore 560001, India.
Natarajamurthy ShilpaDepartment of Studies in Microbiology, University of Mysore, Mysore 570006, India.
Hemanth Kumar Naguvanahalli KrishnappaPost Graduate Department of Botany, Maharani's Science College for Women, JLB Road, Mysuru 570005, India.ORCID 0000-0002-5776-3151
Ana E LedesmaCentro de InvestigaciónenBiofísicaAplicada y Alimentos, Facultad de Ciencias Exactas y Tecnologías (FCEyN), Universidad Nacional de Santiago del Estero (CIBAAL-UNSE-CONICET), Santiago del Estero 4206, Argentina.
Anisha S JainDepartment of Microbiology, JSS Academy of Higher Education and Research, Mysuru 570015, India.ORCID 0000-0003-1998-3556
Ali A ShatiBiology Department, Faculty of Science, King Khalid University, Abha 9004, Saudi Arabia.
Mohammad Y AlfaifiBiology Department, Faculty of Science, King Khalid University, Abha 9004, Saudi Arabia.ORCID 0000-0003-4310-3539
Serag Eldin I ElbehairiBiology Department, Faculty of Science, King Khalid University, Abha 9004, Saudi Arabia.ORCID 0000-0003-4680-3215
Raghu Ram AcharDivision of Biochemistry, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru 570015, India.ORCID 0000-0001-8196-3703
Ekaterina SilinaDepartment of Hospital Surgery, N.I. Pirogov Russian National Research Medical University, Moscow 117997, Russia.ORCID 0000-0002-0246-5149
Victor StupinDepartment of Hospital Surgery, N.I. Pirogov Russian National Research Medical University, Moscow 117997, Russia.
Joaquín Ortega-CastroDepartament de Química, Facultat de Ciences, Universitat de les IllesBalears, E-07122 Palma de Malllorca, Spain.ORCID 0000-0001-8131-0315
Juan FrauDepartament de Química, Facultat de Ciences, Universitat de les IllesBalears, E-07122 Palma de Malllorca, Spain.ORCID 0000-0003-2562-9975
Norma Flores-HolguínLaboratorio Virtual NANOCOSMOS, Departamento de Medio Ambiente y Energía, Centro de Investigaciónen Materiales Avanzados, Chihuahua 31136, Mexico.ORCID 0000-0002-4836-233X
Kestur Nagaraj AmrutheshDepartment of Studies in Botany, University of Mysore, Mysore 570006, India.
Chandan ShivamalluDepartment of Biotechnology and Bioinformatics, JSS Academy of Higher Education and Research, Mysuru 570015, India.ORCID 0000-0002-1886-139X
Daniel Glossman-MitnikLaboratorio Virtual NANOCOSMOS, Departamento de Medio Ambiente y Energía, Centro de Investigaciónen Materiales Avanzados, Chihuahua 31136, Mexico.ORCID 0000-0002-9583-4256
JSS Academy of Higher Education and Research · INKing Khalid University · SAUniversity of Mysore · INCentro de Investigación en Materiales Avanzados · MXPirogov Russian National Research Medical University · RUUniversitat de les Illes Balears · ESAmrita Vishwa Vidyapeetham · INConsejo Nacional de Investigaciones Científicas y Técnicas · ARInstitute of Botany of the Slovak Academy of Sciences · SK
Funding
King Khalid University R.G.P. 2/ 78/ 43
6 · The paper itself
Abstract
The ever-expanding pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has gained attention as COVID-19 and caused an emergency in public health to an unmatched level to date. However, the treatments used are the only options; currently, no effective and licensed medications are available to combat disease transmission, necessitating further research. In the present study, an in silico-based virtual screening of anti-HIV bioactive compounds from medicinal plants was carried out through molecular docking against the main protease (M
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Exploration of Anti-HIV Phytocompounds against SARS-CoV-2 Main Protease: Structure-Based Screening, Molecular Simulation, ADME Analysis and Conceptual DFT Studies. · full record | OpenQuestion