Evidence map›Paper›PMID 36500340›Full record

ArticleMolecules (Basel, Switzerland)2022

Chemical Profiling and Quantification of Potential Bioactive Components in Gandouling Pill by Ultra-High Performance Liquid Chromatography Coupled with Diode Array Detector/Quadruple-Qrbitrap Mass Spectrometry.

Yue Yang, Wenjie Hao, Yulong Yang, Shijie Zhang, Han Wang, Meixia Wang, Ting Dong, Zhanpeng Shang, Wenming Yang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 63% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yue YangGraduate School of Anhui University of Chinese Medicine, Hefei 230038, China.
Wenjie HaoGraduate School of Anhui University of Chinese Medicine, Hefei 230038, China.
Yulong YangGraduate School of Anhui University of Chinese Medicine, Hefei 230038, China.
Shijie ZhangThe First Affifiliated Hospital of Anhui University of Chinese Medicine, Hefei 230022, China.
Han WangThe First Affifiliated Hospital of Anhui University of Chinese Medicine, Hefei 230022, China.
Meixia WangThe First Affifiliated Hospital of Anhui University of Chinese Medicine, Hefei 230022, China.
Ting DongThe First Affifiliated Hospital of Anhui University of Chinese Medicine, Hefei 230022, China.
Zhanpeng ShangSchool of Pharmaceutical Sciences, Peking University, Beijing 100191, China.ORCID 0000-0002-1576-7867
Wenming YangThe First Affifiliated Hospital of Anhui University of Chinese Medicine, Hefei 230022, China.
Anhui University of Traditional Chinese Medicine · CNMinistry of Education of the People's Republic of China · CNPeking University · CN

Funding

Collaborative Innovation Project of Anhui Colleges and Universities GXXT-2020-025National Natural Science Foundation of China 81973825National Natural Science Foundation of China [Regional Innovation and Development Joint Fund] U22A20366
6 · The paper itself

Abstract

Gandouling (GDL) Pill is a novel Traditional Chinese medicinal drug to treat Wilson's disease in clinics. It is composed of six separate herbal medicines, including Rhei Radix ET Rhizoma, Coptidis Rhizoma, Salviae Miltiorrhizae Radix ET Rhizoma, Spatholobi Caulis, Curcumae Rhizoma, and Curcumae Longae Rhizoma. In this study, a strategy was proposed to investigate the chemical constituents and to quantify the potential bioactive components in GDL Pill. Firstly, the mass fragmentation behaviors of representative compounds were investigated, and, in total, 69 compounds were characterized in GDL Pill using full scan/dd-MS

Indexed as

Drugs, Chinese HerbalTandem Mass SpectrometryAnimalsChromatography, High Pressure LiquidMedicine, Chinese TraditionalRatsRhizomeDrugs, Chinese Herbalabsorbed componentsalkaloidsGandouling Pillqualitatively analysisquantitively analysis

Identifiers

PMID36500340
PMCPMC9740684
OpenAlexW4310035814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.