Evidence map›Paper›PMID 36500206›Full record

ArticleMolecules (Basel, Switzerland)2022

Synthesis, In Silico and In Vivo Toxicity Assessment of Functionalized Pyridophenanthridinones via Sequential MW-Assisted Intramolecular Friedel-Crafts Alkylation and Direct C-H Arylation.

Marlyn C Ortiz Villamizar, Carlos E Puerto Galvis, Silvia A Pedraza Rodríguez, Fedor I Zubkov, Vladimir V Kouznetsov

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marlyn C Ortiz VillamizarLaboratorio de Química Orgánica y Biomolecular, CMN, Universidad Industrial de Santander, Parque Tecnológico Guatiguará, Km 2 Vía Refugio, Piedecuesta 681011, Colombia.ORCID 0000-0001-9909-7452
Carlos E Puerto GalvisLaboratorio de Química Orgánica y Biomolecular, CMN, Universidad Industrial de Santander, Parque Tecnológico Guatiguará, Km 2 Vía Refugio, Piedecuesta 681011, Colombia.ORCID 0000-0003-4173-6826
Silvia A Pedraza RodríguezLaboratorio de Química Orgánica y Biomolecular, CMN, Universidad Industrial de Santander, Parque Tecnológico Guatiguará, Km 2 Vía Refugio, Piedecuesta 681011, Colombia.ORCID 0000-0001-9522-352X
Fedor I ZubkovDepartment of Organic Chemistry, Peoples' Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya Street, 117198 Moscow, Russia.ORCID 0000-0002-0289-0831
Vladimir V KouznetsovLaboratorio de Química Orgánica y Biomolecular, CMN, Universidad Industrial de Santander, Parque Tecnológico Guatiguará, Km 2 Vía Refugio, Piedecuesta 681011, Colombia.ORCID 0000-0003-1417-8355

Funding

COLOMBIAN INSTITUTE FOR SCIENCE (Colciencias) project no. 007-2017, cod. 110274558597RUDN University Scientific Projects Grant System project № 025233-2-000
6 · The paper itself

Abstract

A rapid, efficient, and original synthesis of novel pyrido[3,2,1-

Indexed as

ZebrafishAlkylationAnimalsCyclizationcatalyzed direct C–H arylationin silico computational methodsintramolecular Friedel-Crafts alkylationN-aryl-N-(2-bromobenzyl) cinnamamidespyrido[3,2,1-de]phenanthridin-6-oneszebrafish embryos toxicity

Identifiers

PMID36500206
PMCPMC9741109

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.