ReviewMaterials (Basel, Switzerland)2022
Additive Manufactured Magnesium-Based Scaffolds for Tissue Engineering.
Review in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 41 citations in OpenAlex.
- Mechanical Properties and Corrosion Behavior of Biodegradable Metals: Current Challenges.Materials (Basel, Switzerland) · 2026Review
- Using Magnesium and Magnesium-Based Alloys as a Novel Biomaterial to Create Medical Devices by AM Techniques-A Review.Materials (Basel, Switzerland) · 2026Review
- The evaluation of osteoconductive WE43 magnesium as a therapeutic approach for nonunion treatment : a mouse model.Bone & joint research · 2026Article
- Current Options and Future Perspectives for Conversion Coatings on Biodegradable Magnesium Alloys to Control the Biodegradation Rate and Biological Features.Biomimetics (Basel, Switzerland) · 2026Review
- Biofunctional Testing of a Degradable Implant Made by Mg-Nd and Mg-Zn Alloys Used for Bone Defects.Biomimetics (Basel, Switzerland) · 2026Article
- Advances in Titanium-Based Biomaterial for Human Bone Scaffolds: Narrative Review on Design, Fabrication, Surface Engineering, Implantation, and Biological Evaluation.Materials (Basel, Switzerland) · 2025Review
- Suitability of Mg-Nd and Mg-Zn Alloys to Obtain Biodegradable Structures for Bone Defects.Journal of functional biomaterials · 2025Article
- Advancements in biomaterials and bioactive solutions for lumbar spine fusion cages: Current trends and future perspectives.Bioactive materials · 2025Review
- Novel Nanomaterials for Developing Bone Scaffolds and Tissue Regeneration.Nanomaterials (Basel, Switzerland) · 2025Review
- Overview of porous magnesium-based scaffolds: development, properties and biomedical applications.Materials futures · 2025Review
- Application and Perspectives: Magnesium Materials in Bone Regeneration.ACS biomaterials science & engineering · 2024Review
- Challenges and Pitfalls of Research Designs Involving Magnesium-Based Biomaterials: An Overview.International journal of molecular sciences · 2024Review
- Incorporating strontium enriched amorphous calcium phosphate granules in collagen/collagen-magnesium-hydroxyapatite osteochondral scaffolds improves subchondral bone repair.Materials today. Bio · 2024Article
- Mechanical and Computational Fluid Dynamic Models for Magnesium-Based Implants.Materials (Basel, Switzerland) · 2024Article
- High temperature oxidation treated 3D printed anatomical WE43 alloy scaffolds for repairing periarticular bone defects:Bioactive materials · 2024Article
- Three Birds, One Stone: An Osteo-Microenvironment Stage-Regulative Scaffold for Bone Defect Repair through Modulating Early Osteo-Immunomodulation, Middle Neovascularization, and Later Osteogenesis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Bone Regeneration Induced by Patient-Adapted Mg Alloy-Based Scaffolds for Bone Defects: Present and Future Perspectives.Biomimetics (Basel, Switzerland) · 2023Review
- Human Osteoblasts' Response to Biomaterials for Subchondral Bone Regeneration in Standard and Aggressive Environments.International journal of molecular sciences · 2023Article
- Review
- A Review of Biomimetic and Biodegradable Magnetic Scaffolds for Bone Tissue Engineering and Oncology.International journal of molecular sciences · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
Additive manufacturing (AM) is an important technology that led to a high evolution in the manufacture of personalized implants adapted to the anatomical requirements of patients. Due to a worldwide graft shortage, synthetic scaffolds must be developed. Regarding this aspect, biodegradable materials such as magnesium and its alloys are a possible solution because the second surgery for implant removal is eliminated. Magnesium (Mg) exhibits mechanical properties, which are similar to human bone, biodegradability in human fluids, high biocompatibility, and increased ability to stimulate new bone formation. A current research trend consists of Mg-based scaffold design and manufacture using AM technologies. This review presents the importance of biodegradable implants in treating bone defects, the most used AM methods to produce Mg scaffolds based on powder metallurgy, AM-manufactured implants properties, and in vitro and in vivo analysis. Scaffold properties such as biodegradation, densification, mechanical properties, microstructure, and biocompatibility are presented with examples extracted from the recent literature. The challenges for AM-produced Mg implants by taking into account the available literature are also discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.