ArticleMaterials (Basel, Switzerland)2022
Electrospraying of Bio-Based Chitosan Microcapsules Using Novel Mixed Cross-Linker: Experimental and Response Surface Methodology Optimization.
Article in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Electrosprayed Shellac-Salt Nanoparticles for Improved Intestinal Dissolution and pH-Responsive Drug Release.ACS omega · 2026Article
- Preparation of Tea Tree Essential Oil-Chitosan Microcapsules and Its Effect on the Properties of Water-Based Coating.Polymers · 2025Article
- Enhanced methylene blue adsorption using single-walled carbon nanotubes/chitosan-graft-gelatin nanocomposite hydrogels.Scientific reports · 2024Article
- Review on Electrospray Nanoparticles for Drug Delivery: Exploring Applications.Polymers for advanced technologies · 2024Article
- Biohybrid microcapsules based on electrosprayed CS-immobilized nanoZrV for self-healing epoxy coating development.RSC advances · 2024Article
- Article
- Application of Biomedical Microspheres in Wound Healing.International journal of molecular sciences · 2023Review
Corrections and comments
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Authors and funding
4 authors.
Funding
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Abstract
Chitosan microcapsules draw attention due to their biodegradability, biocompatibility, antibacterial behavior, low cost, easy processing, and the capability to be used for different applications. This study utilized the electrospraying technique for the chitosan microcapsules formulation. As a novel cross-linking agent, a mixture of oxalic acid and sodium phosphate dibasic was utilized as a collecting solution for the first time in the electrospraying of chitosan microcapsules. Scanning Electron Microscopy (SEM) was utilized to optimize the spherical morphology and size of the experimentally obtained microcapsules. The different parameters, including chitosan concentration, applied voltage, flow rate, and tip-to-collector (TTC) distance, affecting the microcapsules' size, sphericity, yield, and combined effects were optimized using Surface Responses Methodology (RSM). The Analysis of Variance (ANOVA) was utilized to obtain the impact of each parameter on the process responses. Accordingly, the results illustrated the significant impact of the voltage parameter, with the highest F-values and least
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