Evidence map›Paper›PMID 36499742›Full record

ReviewInternational journal of molecular sciences2022

COVID-19 Vaccines, Effectiveness, and Immune Responses.

Haneen Imad Abufares, Leen Oyoun Alsoud, Mohammad A Y Alqudah, Mohd Shara, Nelson C Soares, Karem H Alzoubi, Waseem El-Huneidi, Yasser Bustanji, Sameh S M Soliman, Mohammad H Semreen

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Mitigating atherosclerosis: Integrating vaccines with gene targets.American heart journal plus : cardiology research and practice · 2025
    Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Uveal effusion syndrome following COVID-19 vaccination.American journal of ophthalmology case reports · 2023
    Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Vaccine Design: An Introduction.Methods in molecular biology (Clifton, N.J.) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Haneen Imad AbufaresCollege of Pharmacy, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.
Leen Oyoun AlsoudCollege of Pharmacy, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.
Mohammad A Y AlqudahCollege of Pharmacy, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.ORCID 0000-0001-7210-7964
Mohd SharaCollege of Pharmacy, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.
Nelson C SoaresCollege of Pharmacy, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.
Karem H AlzoubiCollege of Pharmacy, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.
Waseem El-HuneidiSharjah Institute for Medical Research, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.ORCID 0000-0002-1580-2589
Yasser BustanjiSharjah Institute for Medical Research, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.ORCID 0000-0003-1315-0609
Sameh S M SolimanCollege of Pharmacy, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.ORCID 0000-0002-7691-615X
Mohammad H SemreenCollege of Pharmacy, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.ORCID 0000-0002-0169-7538

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has captivated the globe's attention since its emergence in 2019. This highly infectious, spreadable, and dangerous pathogen has caused health, social, and economic crises. Therefore, a worldwide collaborative effort was made to find an efficient strategy to overcome and develop vaccines. The new vaccines provide an effective immune response that safeguards the community from the virus' severity. WHO has approved nine vaccines for emergency use based on safety and efficacy data collected from various conducted clinical trials. Herein, we review the safety and effectiveness of the WHO-approved COVID-19 vaccines and associated immune responses, and their impact on improving the public's health. Several immunological studies have demonstrated that vaccination dramatically enhances the immune response and reduces the likelihood of future infections in previously infected individuals. However, the type of vaccination and individual health status can significantly affect immune responses. Exposure of healthy individuals to adenovirus vectors or mRNA vaccines causes the early production of antibodies from B and T cells. On the other hand, unhealthy individuals were more likely to experience harmful events due to relapses in their existing conditions. Taken together, aligning with the proper vaccination to a patient's case can result in better outcomes.

Indexed as

COVID-19Viral VaccinesAntibodies, ViralCOVID-19 VaccinesHumansImmunityPandemicsSARS-CoV-2Antibodies, ViralCOVID-19 VaccinesViral VaccinesCOVID-19effectivenessimmune responsesSARS-CoV-2vaccines

Identifiers

PMID36499742
PMCPMC9737588

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.