Evidence map›Paper›PMID 36499713›Full record

ReviewInternational journal of molecular sciences2022

Addressing the Clinical Feasibility of Adopting Circulating miRNA for Breast Cancer Detection, Monitoring and Management with Artificial Intelligence and Machine Learning Platforms.

Lloyd Ling, Ahmed Faris Aldoghachi, Zhi Xiong Chong, Wan Yong Ho, Swee Keong Yeap, Ren Jie Chin, Eugene Zhen Xiang Soo, Jen Feng Khor, Yoke Leng Yong, Joan Lucille Ling and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Lloyd LingLee Kong Chian Faculty of Engineering & Science, Universiti Tunku Abdul Rahman, Kajang 43000, Malaysia.ORCID 0000-0002-3790-6485
Ahmed Faris AldoghachiM. Kandiah Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Kajang 43000, Malaysia.ORCID 0000-0003-3236-1305
Zhi Xiong ChongDivision of Biomedical Sciences, School of Pharmacy, Faculty of Sciences and Engineering, University of Nottingham Malaysia, Semenyih 43500, Malaysia.ORCID 0000-0002-1695-7638
Wan Yong HoDivision of Biomedical Sciences, School of Pharmacy, Faculty of Sciences and Engineering, University of Nottingham Malaysia, Semenyih 43500, Malaysia.ORCID 0000-0001-5768-0738
Swee Keong YeapChina-ASEAN College of Marine Sciences, Xiamen University Malaysia, Sepang 43900, Malaysia.
Ren Jie ChinLee Kong Chian Faculty of Engineering & Science, Universiti Tunku Abdul Rahman, Kajang 43000, Malaysia.ORCID 0000-0001-5422-5123
Eugene Zhen Xiang SooLee Kong Chian Faculty of Engineering & Science, Universiti Tunku Abdul Rahman, Kajang 43000, Malaysia.ORCID 0000-0003-1978-1110
Jen Feng KhorLee Kong Chian Faculty of Engineering & Science, Universiti Tunku Abdul Rahman, Kajang 43000, Malaysia.
Yoke Leng YongDepartment of Computing and Information Systems, Sunway University, Petaling Jaya 47500, Malaysia.
Joan Lucille LingEdson College of Nursing and Health Innovation, Arizona State University, Phoenix, AZ 85004, USA.
Naing Soe YanM. Kandiah Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Kajang 43000, Malaysia.ORCID 0000-0002-8983-3142
Alan Han Kiat OngM. Kandiah Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Kajang 43000, Malaysia.ORCID 0000-0002-1882-7757
Universiti Tunku Abdul Rahman · MYUniversity of Nottingham Malaysia Campus · MYArizona State University · USSunway University · MYXiamen University Malaysia · MY

Funding

UTARRF Cycle 1 2020 IPSR/RMC/UTARRF/2020-C1/A02
6 · The paper itself

Abstract

Detecting breast cancer (BC) at the initial stages of progression has always been regarded as a lifesaving intervention. With modern technology, extensive studies have unraveled the complexity of BC, but the current standard practice of early breast cancer screening and clinical management of cancer progression is still heavily dependent on tissue biopsies, which are invasive and limited in capturing definitive cancer signatures for more comprehensive applications to improve outcomes in BC care and treatments. In recent years, reviews and studies have shown that liquid biopsies in the form of blood, containing free circulating and exosomal microRNAs (miRNAs), have become increasingly evident as a potential minimally invasive alternative to tissue biopsy or as a complement to biomarkers in assessing and classifying BC. As such, in this review, the potential of miRNAs as the key BC signatures in liquid biopsy are addressed, including the role of artificial intelligence (AI) and machine learning platforms (ML), in capitalizing on the big data of miRNA for a more comprehensive assessment of the cancer, leading to practical clinical utility in BC management.

Indexed as

Breast NeoplasmsCirculating MicroRNAMicroRNAsArtificial IntelligenceBiomarkers, TumorFemaleHumansMachine LearningBiomarkers, TumorCirculating MicroRNAMicroRNAsAIbreast cancercirculating miRNAliquid biopsyML

Identifiers

PMID36499713
PMCPMC9736108
OpenAlexW4311662983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.