Evidence map›Paper›PMID 36499705›Full record

ArticleInternational journal of molecular sciences2022

In Vitro Susceptibility of HIV Isolates with High Growth Capability to Antiretroviral Drugs.

Alfredo A Hinay, Kyosuke Kanai, Akeno Tsuneki-Tokunaga, Mizuki Komatsu, Elizabeth O Telan, Seiji Kageyama

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alfredo A HinayDivision of Virology, Department of Microbiology and Immunology, Faculty of Medicine, Tottori University, Yonago 683-8503, Japan.ORCID 0000-0003-4761-1514
Kyosuke KanaiDivision of Virology, Department of Microbiology and Immunology, Faculty of Medicine, Tottori University, Yonago 683-8503, Japan.ORCID 0000-0002-7984-207X
Akeno Tsuneki-TokunagaDivision of Virology, Department of Microbiology and Immunology, Faculty of Medicine, Tottori University, Yonago 683-8503, Japan.
Mizuki KomatsuDivision of Virology, Department of Microbiology and Immunology, Faculty of Medicine, Tottori University, Yonago 683-8503, Japan.
Elizabeth O TelanNational Reference Laboratory, STD AIDS Cooperative Central Laboratory, San Lazaro Hospital, Manila 1003, Metro Manila, Philippines.
Seiji KageyamaDivision of Virology, Department of Microbiology and Immunology, Faculty of Medicine, Tottori University, Yonago 683-8503, Japan.ORCID 0000-0002-5220-6137
Tottori University · JP

Funding

Japan Society for the Promotion of Science 15K08734, 19K10600Tottori University Grant-in-Aid for Scientific Research on Infection Control and Prevention by the International Platform for Dryland Research and Education
6 · The paper itself

Abstract

It has been considered that reduced susceptibility to antiretroviral drugs is influenced by drug adherence, drug tolerance and drug-resistance-related mutations in the HIV genome. In the present study, we assessed the intrinsic high viral growth capability as a potential viral factor that may influence their susceptibility to antiretroviral drugs using an in vitro model. Phytohemagglutinin-activated peripheral blood mononuclear cells (1.5 × 10

Indexed as

Anti-HIV AgentsHIV-1HIV InfectionsDrug Resistance, ViralHumansLeukocytes, MononuclearMutationReverse Transcriptase InhibitorsAnti-HIV AgentsReverse Transcriptase Inhibitorsantiretroviral drugshuman immunodeficiency virusviral growth capability

Identifiers

PMID36499705
PMCPMC9737537
OpenAlexW4311668595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.