Evidence map›Paper›PMID 36499697›Full record

ArticleInternational journal of molecular sciences2022

Genetic Study of Early Onset Parkinson's Disease in Cyprus.

Rana Abu Manneh, Paraskevi P Chairta, Ellie Mitsi, Maria A Loizidou, Andrea N Georgiou, Yiolanda P Christou, Marios Pantzaris, Eleni Zamba-Papanicolaou, Andreas Hadjisavvas

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Mitoepigenetic Alterations in Early-Onset Parkinson's Disease.International journal of molecular sciences · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Rana Abu MannehNeuroepidemiology Department, The Cyprus Institute of Neurology and Genetics, 2371 Nicosia, Cyprus.ORCID 0000-0002-2501-1561
Paraskevi P ChairtaNeuroepidemiology Department, The Cyprus Institute of Neurology and Genetics, 2371 Nicosia, Cyprus.ORCID 0000-0003-2660-0840
Ellie MitsiNeuroepidemiology Department, The Cyprus Institute of Neurology and Genetics, 2371 Nicosia, Cyprus.ORCID 0000-0001-6079-041X
Maria A LoizidouCancer Genetics, Therapeutics & Ultrastructural Pathology Department, The Cyprus Institute of Neurology and Genetics, 2371 Nicosia, Cyprus.ORCID 0000-0003-4503-7758
Andrea N GeorgiouDepartment of Hygiene and Epidemiology, Medical School, University of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0003-4214-3678
Yiolanda P ChristouAcropoleos Medical Center, 2013 Nicosia, Cyprus.
Marios PantzarisNeuroimmunology Department, The Cyprus Institute of Neurology and Genetics, 2371 Nicosia, Cyprus.ORCID 0000-0003-2937-384X
Eleni Zamba-PapanicolaouNeuroepidemiology Department, The Cyprus Institute of Neurology and Genetics, 2371 Nicosia, Cyprus.
Andreas HadjisavvasCancer Genetics, Therapeutics & Ultrastructural Pathology Department, The Cyprus Institute of Neurology and Genetics, 2371 Nicosia, Cyprus.ORCID 0000-0002-5636-0799
Cyprus Institute of Neurology and Genetics · CYUniversity of Ioannina · GR

Funding

TELETHON Cyprus 33173178
6 · The paper itself

Abstract

Parkinson's Disease (PD) is a multifactorial neurodegenerative disease characterized by motor and non-motor symptoms. The etiology of PD remains unclear. However, several studies have demonstrated the interplay of genetic, epigenetic, and environmental factors in PD. Early-onset PD (EOPD) is a subgroup of PD diagnosed between the ages of 21 and 50. Population genetic studies have demonstrated great genetic variability amongst EOPD patients. Hence, this study aimed to obtain a genetic landscape of EOPD in the Cypriot population. Greek-Cypriot EOPD patients (

Indexed as

Neurodegenerative DiseasesParkinson DiseaseAge of OnsetDNA Copy Number VariationsHumansMutationPhenotypeUbiquitin-Protein LigasesUbiquitin-Protein Ligasesearly onset Parkinson’s disease (EOPD)genetic investigationGreek-Cypriot Parkinson’s patients

Identifiers

PMID36499697
PMCPMC9739936
OpenAlexW4311630646

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.