Evidence map›Paper›PMID 36499642›Full record

ArticleInternational journal of molecular sciences2022

Opposing Roles of DCs and iNKT Cells in the Induction of Foxp3 Expression by MLN CD25

Sung Won Lee, Hyun Jung Park, Luc Van Kaer, Seokmann Hong

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Sung Won LeeDepartment of Integrative Bioscience and Biotechnology, Institute of Anticancer Medicine Development, Sejong University, Seoul 05006, Republic of Korea.ORCID 0000-0001-8059-5961
Hyun Jung ParkDepartment of Integrative Bioscience and Biotechnology, Institute of Anticancer Medicine Development, Sejong University, Seoul 05006, Republic of Korea.ORCID 0000-0002-8547-156X
Luc Van KaerDepartment of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.ORCID 0000-0001-5275-2309
Seokmann HongDepartment of Integrative Bioscience and Biotechnology, Institute of Anticancer Medicine Development, Sejong University, Seoul 05006, Republic of Korea.ORCID 0000-0002-4606-9789
Sejong University · KRVanderbilt University · US

Funding

National Research Foundation of Korea NRF-2019R1A2C1009926National Research Foundation of Korea NRF-2021R1I1A1A01051465National Research Foundation of Korea NRF-2021R1I1A1A01054418National Research Foundation of Korea NRF-2022R1A2C1009590
6 · The paper itself

Abstract

We have previously shown that a deficiency of CD1d-restricted invariant natural killer T (iNKT) cells exacerbates dextran sulfate sodium (DSS)-induced colitis in Yeti mice that exhibit IFNγ-mediated hyper-inflammation. Although iNKT cell-deficiency resulted in reduced Foxp3 expression by mesenteric lymph node (MLN) CD4

Indexed as

ColitisDendritic CellsNatural Killer T-CellsAnimalsCD4-Positive T-LymphocytesForkhead Transcription FactorsInterferon-gammaInterleukin-2 Receptor alpha SubunitMiceMice, Inbred C57BLMice, KnockoutTh17 CellsT-Lymphocytes, RegulatoryForkhead Transcription FactorsFoxp3 protein, mouseInterferon-gammaInterleukin-2 Receptor alpha SubunitCD25+CD4+ T cellsdendritic cellsIFNγiNKT cellsTreg cells

Identifiers

PMID36499642
PMCPMC9738888
OpenAlexW4310676583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.