Evidence map›Paper›PMID 36499610›Full record

ArticleInternational journal of molecular sciences2022

Psychedelic-Induced Serotonin 2A Receptor Downregulation Does Not Predict Swim Stress Coping in Mice.

Błażej D Pędzich, Mireia Medrano, An Buckinx, Ilse Smolders, Dimitri De Bundel

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Błażej D PędzichResearch Group Experimental Pharmacology, Department of Pharmaceutical and Pharmacological Sciences, Center for Neurosciences, Vrije Universiteit Brussel, 1090 Brussels, Belgium.
Mireia MedranoResearch Group Experimental Pharmacology, Department of Pharmaceutical and Pharmacological Sciences, Center for Neurosciences, Vrije Universiteit Brussel, 1090 Brussels, Belgium.
An BuckinxResearch Group Experimental Pharmacology, Department of Pharmaceutical and Pharmacological Sciences, Center for Neurosciences, Vrije Universiteit Brussel, 1090 Brussels, Belgium.
Ilse SmoldersResearch Group Experimental Pharmacology, Department of Pharmaceutical and Pharmacological Sciences, Center for Neurosciences, Vrije Universiteit Brussel, 1090 Brussels, Belgium.ORCID 0000-0003-2140-0751
Dimitri De BundelResearch Group Experimental Pharmacology, Department of Pharmaceutical and Pharmacological Sciences, Center for Neurosciences, Vrije Universiteit Brussel, 1090 Brussels, Belgium.
Vrije Universiteit Brussel · BE

Funding

Research Foundation - Flanders FWOKN284Vrije Universiteit Brussel OZR2739Vrije Universiteit Brussel OZR3476
6 · The paper itself

Abstract

Serotoninergic psychedelics such as psilocybin have been reported to elicit a long-lasting reduction in depressive symptoms. Although the main target for serotoninergic psychedelics, serotonin type 2A receptor (5-HT

Indexed as

HallucinogensAmphetaminesAnimalsAntidepressive AgentsMiceReceptor, Serotonin, 5-HT2ASerotoninSwimmingAmphetaminesAntidepressive AgentsHallucinogensReceptor, Serotonin, 5-HT2ASerotonin5-HT2Abehavioral despairDOIdownregulationhead twitchmicemPFCpsychedelicsstress

Identifiers

PMID36499610
PMCPMC9736085
OpenAlexW4310675742

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.