Evidence map›Paper›PMID 36499537›Full record

ArticleInternational journal of molecular sciences2022

Association between 25-OH Vitamin D Deficiency and COVID-19 Severity in Pregnant Women.

Johana Vásquez-Procopio, Johnatan Torres-Torres, Hector Borboa-Olivares, Salvador Espino Y Sosa, Raigam Jafet Martínez-Portilla, Mario Solis-Paredes, Mari-Cruz Tolentino-Dolores, Addy Cecilia Helguera-Repetto, Karla Cecilia Marrufo-Gallegos, Fanis Missirlis and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Johana Vásquez-ProcopioDepartment of Immunobiochemistry, Instituto Nacional de Perinatología, Mexico City 11000, Mexico.
Johnatan Torres-TorresClinical Research Division, Instituto Nacional de Perinatología, Mexico City 11000, Mexico.ORCID 0000-0002-9524-4133
Hector Borboa-OlivaresCommunity Interventions Research Branch, Instituto Nacional de Perinatología, Mexico City 11000, Mexico.
Salvador Espino Y SosaClinical Research Division, Instituto Nacional de Perinatología, Mexico City 11000, Mexico.ORCID 0000-0001-7276-8463
Raigam Jafet Martínez-PortillaClinical Research Division, Instituto Nacional de Perinatología, Mexico City 11000, Mexico.ORCID 0000-0003-4711-3857
Mario Solis-ParedesClinical Research Division, Instituto Nacional de Perinatología, Mexico City 11000, Mexico.ORCID 0000-0003-4529-8296
Mari-Cruz Tolentino-DoloresCoordination of Nutrition and Bioprogramming, Instituto Nacional de Perinatología, Mexico City 11000, Mexico.
Addy Cecilia Helguera-RepettoDepartment of Immunobiochemistry, Instituto Nacional de Perinatología, Mexico City 11000, Mexico.ORCID 0000-0001-6715-9671
Karla Cecilia Marrufo-GallegosDepartment of Gynecology and Obstetrics, Hospital General de México Dr. Eduardo Liceaga, Mexico City 06720, Mexico.
Fanis MissirlisDepartment of Physiology, Biophysics and Neuroscience, Center for Research and Advanced Studies (Cinvestav), Mexico City 07360, Mexico.ORCID 0000-0003-0467-8444
Otilia Perichart-PereraCoordination of Nutrition and Bioprogramming, Instituto Nacional de Perinatología, Mexico City 11000, Mexico.ORCID 0000-0003-1492-5293
Guadalupe Estrada-GutierrezResearch Division, Instituto Nacional de Perinatología, Mexico City 11000, Mexico.ORCID 0000-0001-9551-9021
Instituto Nacional de Perinatología · MXCentro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional · MXHospital General de México · MX

Funding

National Council of Science and Technology FOSISS-2015-3-261661National Institute of Perinatology 2020-1-32 and 3300-11402-01-575-17
6 · The paper itself

Abstract

Evidence from studies in the general population suggests an association between vitamin D insufficiency/deficiency and COVID-19 susceptibility and disease severity. The present study was performed on 165 third-trimester pregnant women at the time of delivery. Seventy-nine women tested negative for SARS-CoV-2. From 86 women testing positive, 32 were asymptomatic, 44 presented a mild form of the disease, and 10 experienced severe symptoms. Serum 25-OH vitamin D levels were measured on blood samples collected on admission. Low vitamin D levels were detected in symptomatic but not asymptomatic COVID-19 patients compared to healthy women (

Indexed as

COVID-19Pregnancy ComplicationsVitamin D DeficiencyFemaleHumansPregnancySARS-CoV-2Vitamin DVitamin Dasymptomaticimmune systempregnancySARS-CoV-2vitamin D deficiency

Identifiers

PMID36499537
PMCPMC9735729
OpenAlexW4311514641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.