Evidence map›Paper›PMID 36499524›Full record

ArticleInternational journal of molecular sciences2022

Biochemical and Biophysical Characterization of the Caveolin-2 Interaction with Membranes and Analysis of the Protein Structural Alteration by the Presence of Cholesterol.

Berta Gorospe, José J G Moura, Carlos Gutierrez-Merino, Alejandro K Samhan-Arias

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Berta GorospeLAQV-REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2829-516 Lisbon, Portugal.
José J G MouraLAQV-REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2829-516 Lisbon, Portugal.
Carlos Gutierrez-MerinoResearch Institute of Molecular Pathology Biomarkers, University of Extremadura, 06006 Badajoz, Spain.ORCID 0000-0003-3673-7007
Alejandro K Samhan-AriasLAQV-REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2829-516 Lisbon, Portugal.ORCID 0000-0001-9602-4848
Rede de Química e Tecnologia · PTInstituto de Investigaciones Biomédicas Sols-Morreale · ESUniversidad de Extremadura · ES

Funding

Ayuda a Grupos de la Junta de Extremadura BBB008- GR21051ERDF under the PT2020 Partnership Agreement POCI-01-0145-FEDER - 007265FCT/MCTES UIDB/04378/2020FCT/MCTES UID/QUI/50006/2020FCT/MCTES for the post-doctoral fellowship grants SFRH/BPD/100069/2014PT2020 Partnership Agreement POCI-01-0145-FEDER - 007265PT2020 Partnership Agreement POCI-01-0145-FEDER-007728
6 · The paper itself

Abstract

Caveolin-2 is a protein suitable for the study of interactions of caveolins with other proteins and lipids present in caveolar lipid rafts. Caveolin-2 has a lower tendency to associate with high molecular weight oligomers than caveolin-1, facilitating the study of its structural modulation upon association with other proteins or lipids. In this paper, we have successfully expressed and purified recombinant human caveolin-2 using

Indexed as

Caveolin 1Escherichia coliCaveolaeCaveolin 2CholesterolHumansLipid BilayersMembrane MicrodomainsCaveolin 1Caveolin 2CholesterolLipid Bilayerscaveolin-1caveolin-2cholesterolmembrane interactionsecondary structure prediction

Identifiers

PMID36499524
PMCPMC9736327
OpenAlexW4311517675

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.